Direct observation of myoglobin structural dynamics from 100 picoseconds to 1 microsecond with picosecond X-ray solution scattering

被引:37
作者
Kim, Kyung Hwan [1 ]
Oang, Key Young [1 ]
Kim, Jeongho [1 ]
Lee, Jae Hyuk [1 ]
Kim, Youngmin [1 ]
Ihee, Hyotcherl [1 ]
机构
[1] Korea Adv Inst Sci & Technol, Ctr Time Resolved Diffract, Dept Chem, Grad Sch Nanosci & Technol WCU, Taejon 305701, South Korea
关键词
CARBON-MONOXIDE; CIRCULAR-DICHROISM; PROTEIN DYNAMICS; LIGAND-BINDING; CRYSTALLOGRAPHY; PHOTODISSOCIATION; SPECTROSCOPY; HEMOGLOBIN; ABSORPTION; COMPLEX;
D O I
10.1039/c0cc01817a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Here we report structural dynamics of equine myoglobin (Mb) in response to the CO photodissociation visualized by picosecond time-resolved X-ray solution scattering. The data clearly reveal new structural dynamics that occur in the timescale of similar to 360 picoseconds (ps) and similar to 9 nanoseconds (ns), which have not been clearly detected in previous studies.
引用
收藏
页码:289 / 291
页数:3
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