Recent advances in electrochemical biosensing schemes using graphene and graphene-based nanocomposites

被引：185

作者：

Vashist, Sandeep Kumar ^{[1
,2
]}

Luong, John H. T. ^{[3
]}

机构：

[1] HSG IMIT, Inst Mikro & Informationstechn, D-79110 Freiberg 79110, Germany

[2] Tech Univ Bergakad Freiberg, IMTEK, Dept Microsyst Engn, Lab MEMS Applicat, D-79110 Freiberg, Germany

[3] Univ Coll Cork, Biol Chem Res Fac ABCRF, Dept Chem & Analyt, Innovat Chromatog Grp,Irish Separat Sci Cluster I, College Pk, MD USA

来源：

CARBON | 2015年 / 84卷

关键词：

GLASSY-CARBON ELECTRODE; NITROGEN-DOPED GRAPHENE; NANOPARTICLES-DECORATED GRAPHENE; MOLECULARLY IMPRINTED POLYMER; NONENZYMATIC GLUCOSE SENSOR; CHEMICAL-VAPOR-DEPOSITION; LABEL-FREE DETECTION; STRIPPING VOLTAMMETRIC DETECTION; SENSITIVE AMPEROMETRIC SENSOR; ENHANCED SENSING PLATFORM;

D O I：

10.1016/j.carbon.2014.12.052

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The last decade has witnessed tremendous advances in the use of graphene and graphene-based nanocomposites for the fabrication of electrochemical (EC) sensors and biosensors with improved analytical performance. With unique and highly desirable morphology, chemical/thermal stability and EC properties, the graphene-based materials are paving way to the implementation of mediatorless EC detection schemes with direct electron transfer. This approach enables the development of highly performed biosensors with respect to detection sensitivity, precision, specificity, and stability. This review provides a comprehensive overview of the field apart from providing intensive information of the fabrication, properties, characterization and EC applications of graphene and its nanocomposites. Two key challenges, the lack of international regulatory guidelines for nanotoxicity analysis and potential mass production of analytical devices, will also be discussed along with the trends in nanobiotechnology and the requirements in healthcare and industrial applications. (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：519 / 550

页数：32

共 423 条

[1] Preparation of NiFe2O4/graphene nanocomposite and its application as a modifier for the fabrication of an electrochemical sensor for the simultaneous determination of tramadol and acetaminophen [J].