Monitoring asthma in children

被引：100

作者：

Pijnenburg, Marille W. ^{[1
]}

Baraldi, Eugenio ^{[2
]}

Brand, Paul L. P. ^{[3
,4
]}

Carlsen, Kai-Hakon ^{[5
,6
]}

Eber, Ernst ^{[7
]}

Frischer, Thomas ^{[8
]}

Hedlin, Gunilla ^{[9
,10
,11
]}

Kulkarni, Neeta ^{[12
,13
]}

Lex, Christiane ^{[14
]}

Makela, Mika J. ^{[15
]}

Mantzouranis, Eva ^{[16
]}

Moeller, Alexander ^{[17
]}

Pavord, Ian ^{[18
]}

Piacentini, Giorgio ^{[19
]}

Price, David ^{[20
]}

Rottier, Bart L. ^{[21
]}

Saglani, Sejal ^{[22
]}

Sly, Peter D. ^{[23
]}

Szefler, Stanley J. ^{[24
,25
]}

Tonia, Thomy ^{[26
]}

Turner, Steve ^{[27
]}

Wooler, Edwina ^{[28
]}

Carlsen, Karin C. Lodrup ^{[29
,30
]}

机构：

[1] Erasmus MC Sophia Childrens Hosp, Dept Paediat Paediat Resp Med, Rotterdam, Netherlands

[2] Univ Padua, Womens & Childrens Hlth Dept, Unit Resp Med & Allergy, Padua, Italy

[3] Isala Hosp, Dept Paediat, Princess Amalia Childrens Ctr, Zwolle, Netherlands

[4] Univ Groningen, Univ Med Ctr Groningen, UMCG Postgrad Sch Med, NL-9713 AV Groningen, Netherlands

[5] Univ Oslo, Inst Clin Med, Dept Paediat, Oslo, Norway

[6] Oslo Univ Hosp, Oslo, Norway

[7] Med Univ Graz, Dept Paediat & Adolescence Med, Resp & Allerg Dis Div, Graz, Austria

[8] Wilhelminenspital Stadt Wien, Dept Paediat & Paediat Surg, Vienna, Austria

[9] Karolinska Inst, Dept Womens & Childrens Hlth, Stockholm, Sweden

[10] Karolinska Inst, Ctr Allergy Res, Stockholm, Sweden

[11] Astrid Lindgren Childrens Hosp, Stockholm, Sweden

[12] Univ Leicester, Leicestershire Partnership Trust, Leicester, Leics, England

[13] Univ Leicester, Dept Infect Immun & Inflammat, Leicester, Leics, England

[14] Univ Hosp Gottingen, Div Pediat Resp Med, Dept Paediat Cardiol & Intens Care Med, Gottingen, Germany

[15] Helsinki Univ Hosp, Skin & Allergy Hosp, Helsinki, Finland

[16] Univ Crete, Univ Hosp Heraklion, Dept Paediat, Iraklion, Greece

[17] Univ Childrens Hosp Zurich, Div Resp Med, Zurich, Switzerland

[18] Univ Oxford, Dept Resp Med, Oxford, England

[19] Univ Verona, Dept Life & Reprod Sci, Paediat Sect, I-37100 Verona, Italy

[20] Univ Aberdeen, Div Appl Hlth Sci, Dept Primary Care Resp Med, Acad Primary Care, Aberdeen, Scotland

[21] Univ Groningen, Univ Med Ctr Groningen, GRIAC Res Inst, Dept Pediat Pulmonol & Allergol, Groningen, Netherlands

[22] Univ London Imperial Coll Sci Technol & Med, Natl Heart & Lung Inst, Leukocyte Biol & Resp Paediat, London, England

[23] Univ Queensland, Queensland Childrens Med Res Inst, Brisbane, Qld, Australia

[24] Childrens Hosp Colorado, Denver, CO USA

[25] Univ Colorado, Denver Sch Med, Denver, CO 80202 USA

[26] Univ Bern, Inst Social & Prevent Med, Bern, Switzerland

[27] Univ Aberdeen, Dept Paediat, Aberdeen, Scotland

[28] Royal Alexandra Childrens Hosp, Brighton, E Sussex, England

[29] Oslo Univ Hosp, Women & Childrens Div, Dept Paediat, Oslo, Norway

[30] Univ Oslo, Fac Med, Dept Paediat, Oslo, Norway

来源：

EUROPEAN RESPIRATORY JOURNAL | 2015年 / 45卷 / 04期

关键词：

EXHALED NITRIC-OXIDE; ENVIRONMENTAL TOBACCO-SMOKE; PROBLEMATIC SEVERE ASTHMA; FORCED EXPIRATORY VOLUME; LUNG-FUNCTION; CHILDHOOD ASTHMA; INHALED CORTICOSTEROIDS; RESPIRATORY SYMPTOMS; AIRWAY INFLAMMATION; BRONCHODILATOR RESPONSE;

D O I：

10.1183/09031936.00088814

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

The goal of asthma treatment is to obtain clinical control and reduce future risks to the patient. To reach this goal in children with asthma, ongoing monitoring is essential. While all components of asthma, such as symptoms, lung function, bronchial hyperresponsiveness and inflammation, may exist in various combinations in different individuals, to date there is limited evidence on how to integrate these for optimal monitoring of children with asthma. The aims of this ERS Task Force were to describe the current practise and give an overview of the best available evidence on how to monitor children with asthma. 22 clinical and research experts reviewed the literature. A modified Delphi method and four Task Force meetings were used to reach a consensus. This statement summarises the literature on monitoring children with asthma. Available tools for monitoring children with asthma, such as clinical tools, lung function, bronchial responsiveness and inflammatory markers, are described as are the ways in which they may be used in children with asthma. Management-related issues, comorbidities and environmental factors are summarised. Despite considerable interest in monitoring asthma in children, for many aspects of monitoring asthma in children there is a substantial lack of evidence.

引用

页码：906 / 925

页数：20

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