Prolapse Surgery: What Kind of Antibiotic Prophylaxis Is Necessary?

被引:6
作者
Illiano, Ester [1 ]
Trama, Francesco [1 ]
Crocetto, Felice [2 ]
Califano, Gianluigi [2 ]
Aveta, Achille [2 ]
Motta, Gloria [3 ]
Pastore, Antonio Luigi [4 ]
Brancorsini, Stefano [5 ]
Fabi, Consuelo [5 ]
Costantini, Elisabetta [1 ]
机构
[1] Univ Perugia, Santa Maria Terni Hosp, Androl & Urogynecol Clin, Terni, Italy
[2] Univ Federico II Naples, Dept Gen & Specializes Surg, Renal Transplantat Nephrol Intens Care & Pain Man, Naples, Italy
[3] Urol Clin, Milan, Italy
[4] Sapienza Univ Rome, Fac Pharm & Med, Urol Unit, Dept Med Surg Sci & Biotechnol, Rome, Italy
[5] Univ Perugia, Dept Expt Med, Sect Terni, Terni, Italy
关键词
Prolapse surgery; Antibiotic prophylaxis; Laparoscopic sacrocolpopexy; Infection mesh; Complication surgery; SACRAL COLPOPEXY; MESH; COMPLICATIONS; ANTERIOR; REPAIR; SACROCOLPOPEXY; TERMINOLOGY; OUTCOMES; RISK;
D O I
10.1159/000517788
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Introduction: The aim of this study was to assess whether antibiotic prophylaxis or therapy is sufficient for laparoscopic or vaginal prolapse surgery with mesh. Methods: This is a single-center prospective study. The study was divided into 3 groups. Protocol A: metronidazole (15 mg/kg) and piperacillin-tazobactam (2 g) 1 h before surgery and, for postoperative treatment, gentamycin (160 mg) 1 h before surgery in a single dose. Metronidazole and piperacillin-tazobactam were administered until hospital discharge. Protocol B: gentamycin and piperacillin-tazobactam in the same manner as group A. Protocol C: clindamycin (600 mg) and gentamicin (160 mg) 1 h before surgery in a single dose. Results: We included 87 consecutive patients who underwent prolapse surgery involving mesh prostheses: 57 by the laparoscopic approach and 30 by the vaginal route. Of these, 30 patients were included in protocol A, 30 in protocol B, and 27 in protocol C. There were no statistically significant differences among the 3 protocols regarding any postoperative complications, except for urinary tract infections that were more in the vaginal approach than in the laparoscopic route, in protocol A (p = 0.002). Conclusions: One-shot prophylaxis can be successfully used in prolapse surgery regardless of the surgical approach.
引用
收藏
页码:771 / 776
页数:6
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