Pharmacogenetics of cancer therapy: Getting personal

被引：99

作者：

Krynetski, EY ^{[1
]}

Evans, WE ^{[1
]}

机构：

[1] St Jude Childrens Res Hosp, Memphis, TN 38105 USA

来源：

AMERICAN JOURNAL OF HUMAN GENETICS | 1998年 / 63卷 / 01期

关键词：

D O I：

10.1086/301941

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

[No abstract available]

引用

页码：11 / 16

页数：6

共 38 条

[11] Genetic predisposition to the metabolism of irinotecan (CPT-11) - Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes [J].

Iyer, L ;

King, CD ;

Whitington, PF ;

Green, MD ;

Roy, SK ;

Tephly, TR ;

Coffman, BL ;

Ratain, MJ .

JOURNAL OF CLINICAL INVESTIGATION, 1998, 101 (04) :847-854

[12] Genetic polymorphism of thiopurine S-methyltransferase: Clinical importance and molecular mechanisms [J].

Krynetski, EY ;

Tai, HL ;

Yates, CR ;

Fessing, MY ;

Loennechen, T ;

Schuetz, JD ;

Relling, MV ;

Evans, WE .

PHARMACOGENETICS, 1996, 6 (04) :279-290

[13] A SINGLE-POINT MUTATION LEADING TO LOSS OF CATALYTIC ACTIVITY IN HUMAN THIOPURINE S-METHYLTRANSFERASE [J].

KRYNETSKI, EY ;

SCHUETZ, JD ;

GALPIN, AJ ;

PUI, CH ;

RELLING, MV ;

EVANS, WE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (04) :949-953

[14]

LENNARD, 1990, J CLIN ONCOL, V8, P567

[15] GENETIC-VARIATION IN RESPONSE TO 6-MERCAPTOPURINE FOR CHILDHOOD ACUTE LYMPHOBLASTIC-LEUKEMIA [J].

LENNARD, L ;

LILLEYMAN, JS ;

VANLOON, J ;

WEINSHILBOUM, RM .

LANCET, 1990, 336 (8709) :225-229

[16] VARIABLE MERCAPTOPURINE METABOLISM AND TREATMENT OUTCOME IN CHILDHOOD LYMPHOBLASTIC-LEUKEMIA [J].

LENNARD, L ;

LILLEYMAN, JS .

JOURNAL OF CLINICAL ONCOLOGY, 1989, 7 (12) :1816-1823

[17] ORAL 6-MERCAPTOPURINE IN CHILDHOOD LEUKEMIA - PARENT DRUG PHARMACOKINETICS AND ACTIVE METABOLITE CONCENTRATIONS [J].

LENNARD, L ;

KEEN, D ;

LILLEYMAN, JS .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1986, 40 (03) :287-292

[18] POLYMORPHIC THIOPURINE METHYLTRANSFERASE IN ERYTHROCYTES IS INDICATIVE OF ACTIVITY IN LEUKEMIC BLASTS FROM CHILDREN WITH ACUTE LYMPHOBLASTIC-LEUKEMIA [J].

MCLEOD, HL ;

RELLING, MV ;

LIU, Q ;

PUI, CH ;

EVANS, WE .

BLOOD, 1995, 85 (07) :1897-1902

[19] AZATHIOPRINE-INDUCED MYELOSUPPRESSION IN THIOPURINE METHYLTRANSFERASE DEFICIENT HEART-TRANSPLANT RECIPIENT [J].

MCLEOD, HL ;

MILLER, DR ;

EVANS, WE .

LANCET, 1993, 341 (8853) :1151-1151

[20] THIOPURINE METHYLTRANSFERASE ACTIVITY IN AMERICAN WHITE SUBJECTS AND BLACK SUBJECTS [J].

MCLEOD, HL ;

LIN, JS ;

SCOTT, EP ;

PUI, CH ;

EVANS, WE .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1994, 55 (01) :15-20

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