Imaging the effects of rTMS-induced cortical plasticity

被引：24
作者：
Stagg, Charlotte J. [1 ]
O'Shea, Jacinta [1 ]
Johansen-Berg, Heidi [1 ]
机构：
[1] Univ Oxford, Dept Clin Neurol, Ctr Funct Magnet Resonance Imaging Brain FMRIB, Oxford, England
来源：
RESTORATIVE NEUROLOGY AND NEUROSCIENCE | 2010年 / 28卷 / 04期
基金：
英国惠康基金;
关键词：
Repetitive transcranial magnetic stimulation; motor cortex; stroke; functional magnetic resonance imaging; magnetic resonance spectroscopy; TRANSCRANIAL MAGNETIC STIMULATION; THETA-BURST-STIMULATION; PRIMARY MOTOR CORTEX; NONINVASIVE BRAIN-STIMULATION; LONG-TERM POTENTIATION; CEREBRAL-BLOOD-FLOW; DORSAL PREMOTOR; CORTICOSPINAL EXCITABILITY; RESONANCE SPECTROSCOPY; DEPENDENT PLASTICITY;
D O I：
10.3233/RNN-2010-0553
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Repetitive Transcranial Magnetic Stimulation (rTMS) paradigms are showing increasing promise as tools for neurorehabilitation in a variety of chronic neurological and psychiatric conditions. However, the mechanisms by which they modulate cortical activation are still not completely understood. In this review we summarize what non-invasive magnetic resonance imaging techniques can tell us about the cortical effects of rTMS - from changes at a cellular level within the stimulated motor cortex, to modulating activation patterns within the wider motor network. We discuss how variation in these effects in stroke patients may inform our understanding of how rTMS could improve function in these patients.
引用
收藏
页码：425 / 436
页数：12
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