Camptocormia in Japanese patients with Parkinson's disease: A multicenter study

被引：40

作者：

Seki, Morinobu

Takahashi, Kazushi ^{[1
]}

Koto, Atsuo ^{[3
]}

Mihara, Ban ^{[4
]}

Morita, Yoko ^{[5
]}

Isozumi, Kazuo

Ohta, Kouichi ^{[6
]}

Muramatsu, Kazuhiro ^{[7
]}

Gotoh, Jun ^{[8
]}

Yamaguchi, Keiji ^{[9
]}

Tomita, Yutaka ^{[10
]}

Sato, Hideki ^{[11
]}

Nihei, Yoshihiro

Iwasawa, Satoko ^{[2
]}

Suzuki, Norihiro

机构：

[1] Keio Univ, Sch Med, Dept Neurol, Shinjuku Ku, Tokyo 1608582, Japan

[2] Keio Univ, Sch Med, Dept Prevent Med & Hlth, Tokyo 1608582, Japan

[3] Yomiuri Land Keiyu Hosp, Dept Neurol, Tokyo, Japan

[4] Mihara Mem Hosp, Dept Neurol, Gunma, Japan

[5] Natl Hosp Org, Dept Neurol, Tokyo Med Ctr, Tokyo, Japan

[6] Tachikawa Hosp, Dept Neurol, Tokyo, Japan

[7] Saiseikai Yokohama City Eastern Hosp, Dept Neurol, Yokohama, Kanagawa, Japan

[8] Saiseikai Cent Hosp, Dept Neurol, Tokyo, Japan

[9] Mito Red Cross Hosp, Dept Neurol, Ibaraki, Japan

[10] Tomita Hosp, Dept Neurol, Aichi, Japan

[11] Saitama Municipal Hosp, Dept Neurol, Saitama, Japan

来源：

MOVEMENT DISORDERS | 2011年 / 26卷 / 14期

关键词：

Parkinson's disease; camptocormia; bent spine; nonmotor symptom; Japanese patients; QUESTIONNAIRE; PATHOGENESIS;

D O I：

10.1002/mds.23955

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objective: The aim of this work was to investigate the prevalence of camptocormia and the clinical characteristics of patients with camptocormia in a large population of PD patients. Background: Although camptocormia has been recognized as a prominent phenomenon in PD, the previous epidemiological reports were limited, especially in terms of sample size. Methods: We evaluated 531 PD patients (disease duration: 7.0 +/- 5.5 years, mean 6 standard deviation). We examined their clinical features and the prevalence of camptocormia. Results: Camptocormia was detected in 22 patients (4.1%) and found in patients who were older and had more severe motor symptoms and a higher levodopa (L-dopa) dose (P < 0.05), compared to the patients without camptocormia. Patients with camptocormia showed significantly higher frequencies of autonomic symptoms, such as constipation and urinary incontinence (P < 0.05). Conclusions: Camptocormia is uncommon in PD and is associated with disease severity, higher L-dopa dose and higher frequencies of autonomic symptoms. (C) 2011 Movement Disorder Society

引用

页码：2567 / 2571

页数：5

共 15 条

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