In utero mouse embryonic imaging with OCT for ophthalmologic research

被引：0

作者：

Syed, Saba H. ^{[1
]}

Larina, Irina V. ^{[2
,3
]}

Dickinson, Mary E. ^{[2
,3
]}

Larin, Kirill V. ^{[1
,2
,3
]}

机构：

[1] Univ Houston, Dept Biomed Engn, Houston, TX 77204 USA

[2] Baylor Coll Med, Dept Mol Physiol & Biophys, Houston, TX 77584 USA

[3] Saratov NG Chernyshevskii State Univ, Dept Opt & Biophoton, Saratov 410026, Russia

来源：

OPHTHALMIC TECHNOLOGIES XXI | 2011年 / 7885卷

关键词：

Optical Coherence Tomography (OCT); embryonic development; eye; in utero; OPTICAL COHERENCE TOMOGRAPHY; EYE;

D O I：

暂无

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Live imaging of an eye during embryonic development in mammalian model is important for understanding dynamic aspects of normal and abnormal eye morphogenesis. In this study, we used Swept Source Optical Coherence Tomography (SS-OCT) for live structural imaging of mouse embryonic eye through the uterine wall. The eye structure was reconstructed in mouse embryos at 13.5 to 17.5 days post coitus (dpc). Despite the limited imaging depth of OCT in turbid tissues, we were able to visualize the whole eye globe at these stages. These results suggest that live in utero OCT imaging is a useful tool to study embryonic eye development in the mouse model.

引用

页数：4

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