In vitro performance of magnesium processed by different routes for bone regeneration applications

被引:6
作者
Carboneras, M. [1 ]
Perez-Maceda, B. T. [2 ]
del Valle, J. A. [1 ]
Garcia-Alonso, M. C. [1 ]
Lozano, R. M. [2 ]
Escudero, M. L. [1 ]
机构
[1] CSIC, CENIM, Ctr Nacl Invest Met, Madrid 28040, Spain
[2] CSIC, Ctr Invest Biol, CIB, Madrid 28040, Spain
关键词
Magnesium; Powder metallurgy; Casting; Fluoride-coating; Biodegradation; Biocompatibility; CORROSION; BIODEGRADATION; SCAFFOLDS;
D O I
10.1016/j.matlet.2011.06.041
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Magnesium processed by powder metallurgy (PM) and casting was investigated for potential use in bone regeneration applications. To reduce its corrosion rate, magnesium was surface-modified by a chemical conversion treatment in hydrofluoric acid (HF). In vitro behaviour was evaluated in terms of biodegradation and osteoblastic cell response. The metallurgical route used to produce magnesium has more significant consequences on biodegradation and biocompatibility than the effects of the surface coating. The coated magnesium processed by casting exhibits the best in vitro performance. (C) 2011 Elsevier B.V. All rights reserved.
引用
收藏
页码:3020 / 3023
页数:4
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