Chemical Compositions and Anticancer Potential of Essential Oil from Greenhouse-cultivated Ocimum basilicum Leaves

被引：20

作者：

Aburjai, T. A. ^{[1
]}

Mansi, K. ^{[2
]}

Azzam, Hanan ^{[3
]}

Alqudah, Dana A. ^{[4
]}

Alshaer, W. ^{[4
]}

Abuirjei, M. ^{[5
]}

机构：

[1] Al Al Bayt Univ, Sch Pharm, Mafraq, Jordan

[2] Al Al Bayt Univ, Fac Sci, Mafraq, Jordan

[3] Univ Jordan, Hamdi Mango Ctr Sci Res, Amman, Jordan

[4] Univ Jordan, Cell Therapy Ctr, Amman, Jordan

[5] Jordan Univ Sci & Technol, Fac Pharm, Irbid, Jordan

来源：

INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES | 2020年 / 82卷 / 01期

关键词：

Basil; Ocimum basilicum; essential oils; greenhouse cultivation; antitumor; cancer; VOLATILE COMPONENTS; ANTIOXIDANT; L;

D O I：

10.36468/pharmaceutical-sciences.637

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

In the current study, the compositions of the essential oil obtained from leaves of Ocimum basilicum 'Cinnamon' grown in Jordan in a greenhouse was analysed. The antitumor activity of the essential oil was examined against three different cancer cell lines including MDA-MB-231, MCF7 and U-87 MG. The hydrodistillation method was used to extract the essential oil from Ocimum basilicum and the chemical components were analyzed and identified using gas chromatography-mass spectroscopy. The dry weight yield of essential oil was 0.50 % (w/w). Thirty-one components representing 97.80 % of the essential oil were identified. The main chemical components revealed the presence of linalool, eugenol, eucalyptol, hinesol, trans-alpha-bergamotene and gamma-cadinene as the major constituents. In conclusion, the essential oil extracted from greenhouse cultivated Ocimum basilicum European chemotype showed potent antitumor activity.

引用

页码：179 / 184

页数：6

共 33 条

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