Successful autologous hematopoietic stem cell transplantation for a patient with rapidly progressive localized scleroderma

被引：2

作者：

Nair, Velu ^{[1
]}

Sharma, Ajay ^{[2
]}

Sharma, Sanjeevan ^{[2
]}

Das, Satyaranjan ^{[2
]}

Bhakuni, Darshan S. ^{[2
]}

Narayanan, Krishnan ^{[2
]}

Nair, Vivek ^{[3
]}

Shankar, Subramanian ^{[1
]}

机构：

[1] Armed Forces Med Coll, Pune 411040, Maharashtra, India

[2] Army Hosp Res & Referral, New Delhi, India

[3] Dr Nairs Skin Clin, New Delhi, India

来源：

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES | 2015年 / 18卷 / 03期

关键词：

autologous; localised scleroderma; stem cell transplantation;

D O I：

10.1111/1756-185X.12555

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Autologous hematopoietic stem cell transplant (HSCT) for rapidly progressive disease has not been reported in localized scleroderma. Our patient, a 16-year-old girl had an aggressive variant of localized scleroderma, mixed subtype (linear-generalized) with Parry Romberg syndrome, with no internal organ involvement, that was unresponsive to immunosuppressive therapy and was causing rapid disfigurement. She was administered autologous HSCT in June 2011 and has maintained drug-free remission with excellent functional status at almost 3.5years of follow-up.

引用

页码：366 / 371

页数：6

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