Successful pregnancy in a Swyer syndrome patient with preexisting hypertension

Objective: To report a case of a successful pregnancy and delivery of a patient with 46,XY pure gonadal dysgenesis (Swyer syndrome) and preexisting chronic hypertension who underwent in vitro fertilization (IVF) and embryo transfer (ET). Design: Case report and review of the literature. Setting: 2nd Department of Obstetrics and Gynecology, University of Athens, Medical School, "Aretaieion" Hospital. Division of Pediatric-Adolescent Gynecology and Reconstructive Surgery. Patient(s): A 35-year-old woman with Swyer syndrome and chronic idiopathic hypertension. Intervention(s): Karyotype analysis due to primary amenorrhea; gonadectomy, hormone therapy, investigation of hypertension, IVF using donor oocytes, embryo transfer and caesarean delivery for fetal distress. Main Outcome Measure(s): Successful pregnancy and live birth. Result(s): We present a rare case of a successful pregnancy of a patient with Swyer syndrome accompanied by idiopathic chronic hypertension. Conclusion(s): A woman with Swyer syndrome, hypoplastic uterus, and chronic hypertension delivered a healthy newborn. (Fertil Steril (R) 2011; 96: e83-5. (C) 2011 by American Society for Reproductive Medicine.)