Modified frailty index predicts postoperative outcomes of spontaneous intracerebral hemorrhage

被引：29

作者：

Imaoka, Yukihiro ^{[1
,2
]}

Kawano, Takayuki ^{[2
]}

Hashiguchi, Akihito ^{[3
]}

Fujimoto, Kenji ^{[2
]}

Yamamoto, Keizou ^{[1
]}

Nishi, Toni ^{[4
]}

Otsuka, Tadahiro ^{[5
]}

Yano, Shigetoshi ^{[2
]}

Mukasa, Akitake ^{[2
]}

机构：

[1] Hitoyoshi Med Ctr, Dept Neurosurg, 35 Oigamicho, Hitoyoshi City, Kumamoto 8688555, Japan

[2] Kumamoto Univ, Grad Sch Med Sci, Dept Neurosurg, 1-1-1 Honjo, Kumamoto, Kumamoto 8608556, Japan

[3] Tokuda Neurosurg Hosp, Dept Neursurg, 1-11248-1 Utsuma, Kanoya, Kagoshima 8930011, Japan

[4] Saiseikai Kumamoto Hosp, Dept Neurosurg, 5-3-1 Chikami, Kumamoto, Kumamoto 8614193, Japan

[5] Natl Med Org Kumamoto Med Ctr, Dept Neurosurg, 1-5 Ninomaru, Kumamoto, Kumamoto 8600008, Japan

来源：

CLINICAL NEUROLOGY AND NEUROSURGERY | 2018年 / 175卷

关键词：

Frailty; ICH score; Intracerebral hemorrhage; Modified frailty index; Postoperative outcome; Surgical treatment; PREOPERATIVE FRAILTY; MORTALITY; COMPLICATIONS; MORBIDITY; RISK; LIFE; CARE;

D O I：

10.1016/j.clineuro.2018.11.004

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objectives: Frailty is an indispensable concept among elderly. The purpose of this study was to determine the association between modified frailty index (mFI) and the postoperative outcome of surgery for spontaneous intracerebral hemorrhage (sICH). Patients and methods: Outcome measures included an unfavorable outcome (modified Rankin Scale score of 4-6) or mortality at 6-8 months after hemorrhage. The prognostic ability of mFI was assessed by comparing adjusted and nonadjusted effects with the Hemphill's ICH score. The performance of the ICH score combined with mFl was assessed for discriminative ability. Results: In total, 156 patients satisfied the inclusion criteria. Multivariate analyses revealed that higher mFI was significantly associated with an unfavorable outcome (p-value = 0.004) and mortality (p-value < 0.001). Compared with the ICH score alone, the ICH score combined with mFI revealed significantly higher discriminative ability for predicting postoperative outcome. Conclusion: mFI was a useful and reliable predictor of postoperative unfavorable outcome for sICH. Frailty may be an important essence to be considered before operation for sICS in the aging society.

引用

页码：137 / 143

页数：7

共 25 条

[1] Frailty: An emerging Geriatric syndrome [J].