Nonalcoholic Fatty Liver Disease

被引：41

作者：

Sweet, Patrick H. ^{[1
]}

Khoo, Teresa ^{[2
]}

Nguyen, Steven ^{[2
]}

机构：

[1] Univ Calif Riverside, Family Med, 555 Tachevah Dr,2E-204, Palm Springs, CA 92262 USA

[2] Univ Calif Riverside, Family Med Residency Palm Springs, 555 Tachevah Dr,2E-204, Palm Springs, CA 92262 USA

来源：

PRIMARY CARE | 2017年 / 44卷 / 04期

关键词：

Nonalcoholic fatty liver disease (NAFLD); Nonalcoholic steatohepatitis (NASH); Liver disease; Metabolic disease; Dyslipidemia; Insulin resistance; Steatosis; DIAGNOSIS;

D O I：

10.1016/j.pop.2017.07.003

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Nonalcoholic fatty liver disease (NAFLD) defines a condition of hepatic steatosis with or without hepatic injury. NAFLD is increasing in prevalence worldwide and presents a public health burden. Most patients are asymptomatic, although some present with fatigue and right upper quadrant pain. NAFLD is discovered incidentally when patients have elevated liver enzymes or fatty liver is seen on imaging modalities. Imaging studies can confirm fatty deposits in the liver, but needle biopsy is needed to determine the degree of inflammation. The mainstay of treatment is weight loss and controlling diabetes and hyperlipidemia. Liver transplantation is considered when disease progresses to cirrhosis.

引用

页码：599 / +

页数：11

共 26 条

[1] Non-alcoholic fatty liver disease: The diagnosis and management [J].

Abd El-Kader, Shehab M. ;

El-Den Ashmawy, Eman M. Salah .

WORLD JOURNAL OF HEPATOLOGY, 2015, 7 (06) :846-858

[2]

Bayard M, 2006, AM FAM PHYSICIAN, V73, P1961

[3] Current treatment options for nonalcoholic fatty liver disease and nonalcoholic steatohepatitis [J].

Beaton, Melanie D. .

CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2012, 26 (06) :353-357

[4] Epidemiology and natural history of non-alcoholic fatty liver disease (NAFLD) [J].

Bellentani, Stefano ;

Marino, Mariano .

ANNALS OF HEPATOLOGY, 2009, 8 :S4-S8

[5]

Brunt E.M., 2009, SURG PATHOLOGY GI TR

[6] The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association [J].

Chalasani, Naga ;

Younossi, Zobair ;

Lavine, Joel E. ;

Diehl, Anna Mae ;

Brunt, Elizabeth M. ;

Cusi, Kenneth ;

Charlton, Michael ;

Sanyal, Arun J. .

HEPATOLOGY, 2012, 55 (06) :2005-2023

[7] The Spontaneous Course of Liver Enzymes and Its Correlation in Nonalcoholic Fatty Liver Disease [J].

Charatcharoenwitthaya, Phunchai ;

Lindor, Keith D. ;

Angulo, Paul .

DIGESTIVE DISEASES AND SCIENCES, 2012, 57 (07) :1925-1931

[8] Association of the Ratio of Early Mitral Inflow Velocity to the Global Diastolic Strain Rate with a Rapid Renal Function Decline in Atrial Fibrillation [J].

Chen, Szu-Chia ;

Lee, Wen-Hsien ;

Hsu, Po-Chao ;

Lee, Chee-Siong ;

Lee, Meng-Kuang ;

Yen, Hsueh-Wei ;

Lin, Tsung-Hsien ;

Voon, Wen-Chol ;

Lai, Wen-Ter ;

Sheu, Sheng-Hsiung ;

Su, Ho-Ming .

PLOS ONE, 2016, 11 (01)

[9] Nonalcoholic fatty liver disease: From steatosis to cirrhosis [J].

Farrell, GC ;

Larter, CZ .

HEPATOLOGY, 2006, 43 (02) :S99-S112

[10] Design and validation of a histological scoring system for nonalcoholic fatty liver disease [J].

Kleiner, DE ;

Brunt, EM ;

Van Natta, M ;

Behling, C ;

Contos, MJ ;

Cummings, OW ;

Ferrell, LD ;

Liu, YC ;

Torbenson, MS ;

Unalp-Arida, A ;

Yeh, M ;

McCullough, AJ ;

Sanyal, AJ .

HEPATOLOGY, 2005, 41 (06) :1313-1321

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