A multicenter phase I/II study of enzalutamide in Japanese patients with castration-resistant prostate cancer

被引:7
|
作者
Akaza, Hideyuki [1 ]
Uemura, Hirotsugu [2 ]
Tsukamoto, Taiji [3 ]
Ozono, Seiichiro [4 ]
Ogawa, Osamu [5 ]
Sakai, Hideki [6 ]
Oya, Mototsugu [7 ]
Namiki, Mikio [8 ]
Fukasawa, Satoshi [9 ]
Yamaguchi, Akito [10 ]
Uemura, Hiroji [11 ]
Ohashi, Yasuo [12 ]
Maeda, Hideki [13 ]
Saito, Atsushi [13 ]
Takeda, Kentaro [13 ]
Naito, Seiji [10 ]
机构
[1] Univ Tokyo, Strateg Invest Comprehens Canc Network, Meguro Ku, 4-6-1 Komaba, Tokyo 1538904, Japan
[2] Kinki Univ, Dept Urol, Fac Med, 377-2 Ono Higashi, Osakasayama 5898511, Japan
[3] Sapporo Med Univ, Dept Urol, Sch Med, S1 W17 Chuo Ku, Sapporo, Hokkaido 0608556, Japan
[4] Hamamatsu Univ Sch Med, Dept Urol, Higashi Ku, 1-20-1 Handayama, Hamamatsu, Shizuoka 4313192, Japan
[5] Kyoto Univ, Dept Urol, Grad Sch Med, Sakyo Ku, Yoshida Konoe Cho, Kyoto 6068501, Japan
[6] Nagasaki Univ, Dept Urol, Grad Sch Biomed Sci, 1-7-1 Sakamoto, Nagasaki 8528501, Japan
[7] Keio Univ, Dept Urol, Sch Med, Shinjuku Ku, 35 Shinanomachi, Tokyo 1608582, Japan
[8] Kanazawa Univ, Dept Integrat Canc Therapy & Urol, Grad Sch Med Sci, 13-1 Takara Machi, Kanazawa, Ishikawa 9208641, Japan
[9] Chiba Canc Ctr, Dept Urol, Chuo Ku, 666-2 Nitona Cho, Chiba 2608717, Japan
[10] Harasanshin Hosp, Div Urol, Hakata Ku, 1-8 Taihakumachi, Fukuoka 8120033, Japan
[11] Yokohama City Univ, Dept Urol & Renal Transplantat, Med Ctr, Minami Ku, 4-57 Urafune, Yokohama, Kanagawa 2320024, Japan
[12] Chuo Univ, Dept Integrated Sci & Engn Sustainable Soc, Bunkyo Ku, 1-13-27 Kasuga, Tokyo 1128551, Japan
[13] Astellas Pharma Inc, Chuo Ku, 2-5-1 Nihonbashi Honcho, Tokyo 1038411, Japan
关键词
Androgen receptor inhibitor; Enzalutamide; Metastatic castration-resistant prostate cancer; ABIRATERONE ACETATE; ANTITUMOR-ACTIVITY; INCREASED SURVIVAL; CLINICAL ACTIVITY; DOCETAXEL; THERAPY; TRIAL; PREDNISOLONE; MITOXANTRONE; ANTIANDROGEN;
D O I
10.1007/s10147-016-0952-6
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Trial registration: ClinicalTrials.gov NCT01284920.
引用
收藏
页码:773 / 782
页数:10
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