Gene Expression Profiling in Rodent Models for Schizophrenia

被引：0
作者：
Van Schijndel, Jessica E.
Martens, Gerard J. M.
机构：
[1] Radboud Univ Nijmegen, Dept Mol Anim Physiol, Donders Inst Brain Cognit & Behav, Ctr Neurosci,Fac Sci, NL-6525 GA Nijmegen, Netherlands
[2] Radboud Univ Nijmegen, Fac Sci, NCMLS, NL-6525 GA Nijmegen, Netherlands
来源：
CURRENT NEUROPHARMACOLOGY | 2010年 / 8卷 / 04期
关键词：
Animal model; behavior; genetics; microarray; mRNA expression; neurodevelopment; pharmacology; CAUSES DIFFERENTIAL EXPRESSION; ANTIPSYCHOTIC-DRUG-TREATMENT; PRENATAL VIRAL-INFECTION; POTENTIAL ANIMAL-MODEL; MICROARRAY ANALYSIS; DNA MICROARRAY; MESSENGER-RNA; KNOCKOUT MICE; RAT MODEL; NEURODEVELOPMENTAL DISORDERS;
D O I：
暂无
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The complex neurodevelopmental disorder schizophrenia is thought to be induced by an interaction between predisposing genes and environmental stressors. In order to get a better insight into the aetiology of this complex disorder, animal models have been developed. In this review, we summarize mRNA expression profiling studies on neurodevelopmental, pharmacological and genetic animal models for schizophrenia. We discuss parallels and contradictions among these studies, and propose strategies for future research.
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页码：382 / 393
页数：12
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