Double network hydrogel for tissue engineering

被引：139

作者：

Gu, Zhipeng ^{[1
,2
]}

Huang, Keqing ^{[1
]}

Luo, Yan ^{[3
]}

Zhang, Laibao ^{[4
]}

Kuang, Tairong ^{[5
]}

Chen, Zhou ^{[6
]}

Liao, Guochao ^{[7
]}

机构：

[1] Sun Yat Sen Univ, Sch Engn, Dept Biomed Engn, Guangzhou, Guangdong, Peoples R China

[2] Sichuan Univ, State Key Lab Polymer Mat Engn, Chengdu, Sichuan, Peoples R China

[3] West Virginia Univ, Dept Chem Engn, Morgantown, WV 26506 USA

[4] Louisiana State Univ, Cain Dept Chem Engn, Baton Rouge, LA 70803 USA

[5] South China Univ Technol, Minist Educ, Key Lab Polymer Proc Engn, Guangzhou, Guangdong, Peoples R China

[6] Nanjing Tech Univ, Sch Mech & Power Engn, Nanjing 211800, Jiangsu, Peoples R China

[7] Guangzhou Univ Chinese Med, Int Inst Translat Chinese Med, Guangzhou 510006, Guangdong, Peoples R China

来源：

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY | 2018年 / 10卷 / 06期

基金：

中国国家自然科学基金; 中国博士后科学基金;

关键词：

bone construction; cartilage repair; double network; hydrogels; tissue engineering; HIGH-TOUGHNESS; HIGH-STRENGTH; MECHANICAL-PROPERTIES; PHYSICAL HYDROGELS; HYBRID HYDROGELS; SCAFFOLD DESIGN; BIOMATERIALS; REGENERATION; CHITOSAN; GELATIN;

D O I：

10.1002/wnan.1520

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Double network (DN) hydrogels, a kind of promising soft and tough hydrogels, are produced by two unique contrasting networks with designed network entanglement burst into the field of materials science as versatile functional systems for a very broad range of applications. A part of the DN hydrogels is characterized by extraordinary mechanical properties providing efficient biocompatible and high strength for holding considerable promise in tissue engineering. Following DN hydrogels principles and consideration of biomedical applications, we provide an overall view of the present various DN hydrogels and look forward to the future of DN hydrogels for tissue engineering. In this review, the preparation methods, structure, properties, current situation, and challenges are mainly discussed for the purpose of tissue engineering. This article is categorized under: Implantable Materials and Surgical Technologies > Nanomaterials and Implants Implantable Materials and Surgical Technologies > Nanotechnology in Tissue Repair and Replacement

引用

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