Seroprevalence of neutralizing antibodies to adenovirus type 5 among children in India: Implications for recombinant adenovirus-based Vaccines

被引：28
作者：
Appaiahgari, Mohan Babu
Pandey, Ravindra Mohan
Vrati, Sudhanshu
机构：
[1] Natl Inst Immunol, JNU Complex, New Delhi 110067, India
[2] All India Inst Med Sci, Dept Biostat, New Delhi 110016, India
来源：
CLINICAL AND VACCINE IMMUNOLOGY | 2007年 / 14卷 / 08期
关键词：
D O I：
10.1128/CVI.00173-07
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We determined the levels of adenovirus 5 (Ad5) neutralizing antibodies in children in India less than 2 years of age. The results clearly show an age-dependent increase in Ad5-specitic immunity, with 7- to 12-month-old children having the lowest levels of Ad5 immunity. This opens up the scope for the use of recombinant Ad5-based vaccines in this age group.
引用
收藏
页码：1053 / 1055
页数：3
相关论文
共 50 条
[41]   A STUDY OF ILLNESS IN A GROUP OF CLEVELAND FAMILIES .15. ACQUISITION OF TYPE-SPECIFIC ADENOVIRUS ANTIBODIES IN THE 1ST 5 YEARS OF LIFE - IMPLICATIONS FOR THE USE OF ADENOVIRUS VACCINE [J].
JORDAN, WS ;
BADGER, GF ;
DINGLE, JH .
NEW ENGLAND JOURNAL OF MEDICINE, 1958, 258 (21) :1041-1044
[42]   A Replication-Defective Human Type 5 Adenovirus-Based Trivalent Vaccine Confers Complete Protection against Plague in Mice and Nonhuman Primates [J].
Sha, Jian ;
Kirtley, Michelle L. ;
Klages, Curtis ;
Erova, Tatiana E. ;
Telepnev, Maxim ;
Ponnusamy, Duraisamy ;
Fitts, Eric C. ;
Baze, Wallace B. ;
Sivasubramani, Satheesh K. ;
Lawrence, William S. ;
Patrikeev, Igor ;
Peel, Jennifer E. ;
Andersson, Jourdan A. ;
Kozlova, Elena V. ;
Tiner, Bethany L. ;
Peterson, Johnny W. ;
McWilliams, David ;
Patel, Snehal ;
Rothe, Eric ;
Motin, Vladimir L. ;
Chopra, Ashok K. .
CLINICAL AND VACCINE IMMUNOLOGY, 2016, 23 (07) :586-600
[43]   Designed recombinant adenovirus type 5 vector induced envelope-specific CD8+ cytotoxic T lymphocytes and cross-reactive neutralizing antibodies against human immunodeficiency virus type 1 [J].
Ura, Takehiro ;
Yoshida, Atsushi ;
Xin, Ke-Qin ;
Yoshizaki, Shinji ;
Yashima, Sayaka ;
Abe, Shinya ;
Mizuguchi, Hiroyuki ;
Okuda, Kenji .
JOURNAL OF GENE MEDICINE, 2009, 11 (02) :139-149
[44]   Glycan Masking of Hemagglutinin for Adenovirus Vector and Recombinant Protein Immunizations Elicits Broadly Neutralizing Antibodies against H5N1 Avian Influenza Viruses [J].
Lin, Shih-Chang ;
Liu, Wen-Chun ;
Jan, Jia-Tsrong ;
Wu, Suh-Chin .
PLOS ONE, 2014, 9 (03)
[45]   An adjuvanted adenovirus 5-based vaccine elicits neutralizing antibodies and protects mice against chikungunya virus-induced footpad swelling [J].
Dora, Emery G. ;
Rossi, Shannan L. ;
Weaver, Scott C. ;
Tucker, Sean N. ;
Mateo, Roberto .
VACCINE, 2019, 37 (24) :3146-3150
[46]   Circulation of a Novel Pattern of Infections by Enteric Adenovirus Serotype 41 among Children below 5 Years of Age in Kolkata, India [J].
Dey, Rakhi Sharma ;
Ghosh, Santanu ;
Chawla-Sarkar, Mamta ;
Panchalingam, Sandra ;
Nataro, James P. ;
Sur, Dipika ;
Manna, Byomkesh ;
Ramamurthy, Thandavarayan .
JOURNAL OF CLINICAL MICROBIOLOGY, 2011, 49 (02) :500-505
[47]   Evaluation of recombinant adenovirus vaccines based on glycoprotein D and truncated UL25 against herpes simplex virus type 2 in mice [J].
Liu, Wei ;
Zhou, Yan ;
Wang, Ziyan ;
Zhang, Zeqiang ;
Wang, Qizhi ;
Su, Weiheng ;
Chen, Yan ;
Zhang, Yan ;
Gao, Feng ;
Jiang, Chunlai ;
Kong, Wei .
MICROBIOLOGY AND IMMUNOLOGY, 2017, 61 (05) :176-184
[48]   International epidemiology of human pre-existing adenovirus (Ad) type-5, type-6, type-26 and type-36 neutralizing antibodies: Correlates of high Ad5 titers and implications for potential HIV vaccine trials [J].
Mast, T. Christopher ;
Kierstead, Lisa ;
Gupta, Swati B. ;
Nikas, Alexander A. ;
Kallas, Esper G. ;
Novitsky, Vladimir ;
Mbewe, Bernard ;
Pitisuttithum, Punee ;
Schechter, Mauro ;
Vardas, Eftyhia ;
Wolfe, Nathan D. ;
Aste-Amezaga, Miguel ;
Casimiro, Danilo R. ;
Coplan, Paul ;
Straus, Walter L. ;
Shiver, John W. .
VACCINE, 2010, 28 (04) :950-957
[49]   Pooled Analysis of the Effect of Pre-Existing Ad5 Neutralizing Antibodies on the Immunogenicity of Adenovirus Type 5 Vector-Based COVID-19 Vaccine from Eight Clinical Trials [J].
Liu, Wenqing ;
Li, Yuqing ;
Li, Xiaolong ;
Wang, Feiyu ;
Qi, Runjie ;
Zhu, Tao ;
Li, Jingxin .
VACCINES, 2025, 13 (03)
[50]   Immunogenicity of Recombinant Adenovirus Type 5 Vector-Based Ebola Vaccine Expressing Glycoprotein from the 2014 Epidemic Strain in Mice [J].
Wang, Ling ;
Liu, Jingjing ;
Kong, Yan ;
Hou, Lihua ;
Li, Yuhua .
HUMAN GENE THERAPY, 2018, 29 (01) :87-95
12345