Seroprevalence of neutralizing antibodies to adenovirus type 5 among children in India: Implications for recombinant adenovirus-based Vaccines

被引：28
|
作者：
Appaiahgari, Mohan Babu
Pandey, Ravindra Mohan
Vrati, Sudhanshu
机构：
[1] Natl Inst Immunol, JNU Complex, New Delhi 110067, India
[2] All India Inst Med Sci, Dept Biostat, New Delhi 110016, India
来源：
CLINICAL AND VACCINE IMMUNOLOGY | 2007年 / 14卷 / 08期
关键词：
D O I：
10.1128/CVI.00173-07
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We determined the levels of adenovirus 5 (Ad5) neutralizing antibodies in children in India less than 2 years of age. The results clearly show an age-dependent increase in Ad5-specitic immunity, with 7- to 12-month-old children having the lowest levels of Ad5 immunity. This opens up the scope for the use of recombinant Ad5-based vaccines in this age group.
引用
收藏
页码：1053 / 1055
页数：3
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