Synthesis of novel diethyl indolylphosphonates and tetraethyl indolyl-1,1-bisphosphonates by Michael addition

被引：13

作者：

Couthon-Gourvès, H ^{[1
]}

Simon, G ^{[1
]}

Haelters, JP ^{[1
]}

Corbel, B ^{[1
]}

机构：

[1] UFR Sci & Tech, Lab Chim Hetero Organ, F-29238 Brest 3, France

来源：

SYNTHESIS-STUTTGART | 2006年 / 1卷 / 01期

关键词：

indoles; phosphorous compounds; bisphosphonates; Michael additions; heterocycles;

D O I：

10.1055/s-2005-921757

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

As series of (1H-indol-3-yl)phosphonates and bisphosphonates as well as (1H-indol-1-yl)phosphonates and bisphosphonates was prepared via the Michael addition of substituted indoles with electron-deficient olefins like ethyl 2-(diethoxyphosphoryl)acrylate and tetraethyl ethenylidene-1,1-bisphosphonate. The chemo selectivity of the reaction is discussed.

引用

页码：81 / 88

页数：8

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