Semen dysbiosis-just a male problem?

被引：4

作者：

Morawiec, Emilia ^{[1
,2
,3
]}

Czerwinski, Michal ^{[2
,4
]}

Bednarska-Czerwinska, Anna ^{[2
,5
]}

Wiczkowski, Andrzej ^{[1
]}

机构：

[1] Univ Technol Katowice, Fac Med, Dept Microbiol, Katowice, Poland

[2] Gyncentrum Sp zoo, Lab Mol Biol & Virol, Katowice, Poland

[3] Univ Technol Katowice, Fac Med, Dept Histol Cytophysiol & Embryol, Katowice, Poland

[4] Amer Med Clin, Katowice, Poland

[5] Univ Technol Katowice, Fac Med, Katowice, Poland

来源：

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY | 2022年 / 12卷

关键词：

semen; microbiome; dysbiosis; infertility; sequencing; MALE-INFERTILITY; ACTINOBACULUM-SCHAALII; MICROBIOME;

D O I：

10.3389/fcimb.2022.815786

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Seminal microflora is crucial to male fertility. Dysbiosis-disturbance of quantitative ratios of individual bacteria or appearance of pathogenic species-rarely results in symptomatic disease. Inflammation results in decreased sperm production, lower motility, or morphological changes and, in the long term, can cause ejaculatory duct obstruction, leading to infertility. Moreover, it may cause infection of the partner's female genital tract. Dysbiosis in both partners results in fertility problems, disorders in embryo implantation, or miscarriages. In addition, chronic inflammation of the male genitourinary system may accelerate the appearance of antisperm antibodies. A comprehensive examination of seminal microflora can clarify the causes of infertility or prevent pathological conditions that affect seminal parameters. Seminal microflora as a direct impact on fertility problems as well as a decrease in the effectiveness of assisted reproduction methods, insemination, or in vitro procedures.

引用

页数：8

共 46 条

[31] Characterization of microbiota in male infertility cases uncovers differences in seminal hyperviscosity and oligoasthenoteratozoospermia possibly correlated with increased prevalence of infectious bacteria [J].

Monteiro, Catarina ;

Marques, Patricia I. ;

Cavadas, Bruno ;

Damiao, Isabel ;

Almeida, Vasco ;

Barros, Nuno ;

Barros, Alberto ;

Carvalho, Filipa ;

Gomes, Silvia ;

Seixas, Susana .

AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 2018, 79 (06)

[32] The presence of bacteria species in semen and sperm quality [J].

Moretti, Elena ;

Capitani, Serena ;

Figura, Natale ;

Pammolli, Andrea ;

Federico, Maria Grazia ;

Giannerini, Valentina ;

Collodel, Giulia .

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS, 2009, 26 (01) :47-56

[33] Effects of bacteria on male fertility: Spermatogenesis and sperm function [J].

Oghbaei, Hajar ;

Rezaei, Yeganeh Rastgar ;

Nikanfar, Saba ;

Zarezadeh, Reza ;

Sadegi, Mohammadreza ;

Latifi, Zeinab ;

Nouri, Mohammad ;

Fattahi, Amir ;

Ahmadi, Yadollah ;

Bleisinger, Nathalie .

LIFE SCIENCES, 2020, 256

[34]

Okwelogu S.I., 2020, SEXUAL REPROD HLTH, V15, DOI [10.1101/2020.10.22.20215988, DOI 10.1101/2020.10.22.20215988]

[35] Microbiological Evaluation and Sperm DNA Fragmentation in Semen Samples of Patients Undergoing Fertility Investigation [J].

Pagliuca, Chiara ;

Cariati, Federica ;

Bagnulo, Francesca ;

Scaglione, Elena ;

Carotenuto, Consolata ;

Farina, Fabrizio ;

D'Argenio, Valeria ;

Carraturo, Francesca ;

D'Aprile, Paola ;

Vitiello, Mariateresa ;

Strina, Ida ;

Alviggi, Carlo ;

Colicchio, Roberta ;

Tomaiuolo, Rossella ;

Salvatore, Paola .

GENES, 2021, 12 (05)

[36] Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development [J].

Pan, Wei-Hung ;

Sommer, Felix ;

Falk-Paulsen, Maren ;

Ulas, Thomas ;

Best, Philipp ;

Fazio, Antonella ;

Kachroo, Priyadarshini ;

Luzius, Anne ;

Jentzsch, Marlene ;

Rehman, Ateequr ;

Mueller, Fabian ;

Lengauer, Thomas ;

Walter, Joern ;

Kuenzel, Sven ;

Baines, John F. ;

Schreiber, Stefan ;

Franke, Andre ;

Schultze, Joachim L. ;

Backhed, Fredrik ;

Rosenstiel, Philip .

GENOME MEDICINE, 2018, 10

[37]

Pasquale S., 2021, GLOB J FERTIL RES, V6, DOI [10.17352/gjfr.000019, DOI 10.17352/GJFR.000019]

[38]

Restrepo Arenas V., 2021, REV UROL COLOMB COLO, V30, P140, DOI [10.1055/s-0040-1721325, DOI 10.1055/S-0040-1721325]

[39]

Salonia A., 2021, EAU GUIDELINES SEXUA

[40] What human sperm RNA-Seq tells us about the microbiome [J].

Swanson, Grace M. ;

Moskovtsev, Sergey ;

Librach, Clifford ;

Pilsner, J. Richard ;

Goodrich, Robert ;

Krawetz, Stephen A. .

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS, 2020, 37 (02) :359-368

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