Semen dysbiosis-just a male problem?

被引:4
作者
Morawiec, Emilia [1 ,2 ,3 ]
Czerwinski, Michal [2 ,4 ]
Bednarska-Czerwinska, Anna [2 ,5 ]
Wiczkowski, Andrzej [1 ]
机构
[1] Univ Technol Katowice, Fac Med, Dept Microbiol, Katowice, Poland
[2] Gyncentrum Sp zoo, Lab Mol Biol & Virol, Katowice, Poland
[3] Univ Technol Katowice, Fac Med, Dept Histol Cytophysiol & Embryol, Katowice, Poland
[4] Amer Med Clin, Katowice, Poland
[5] Univ Technol Katowice, Fac Med, Katowice, Poland
来源
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY | 2022年 / 12卷
关键词
semen; microbiome; dysbiosis; infertility; sequencing; MALE-INFERTILITY; ACTINOBACULUM-SCHAALII; MICROBIOME;
D O I
10.3389/fcimb.2022.815786
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Seminal microflora is crucial to male fertility. Dysbiosis-disturbance of quantitative ratios of individual bacteria or appearance of pathogenic species-rarely results in symptomatic disease. Inflammation results in decreased sperm production, lower motility, or morphological changes and, in the long term, can cause ejaculatory duct obstruction, leading to infertility. Moreover, it may cause infection of the partner's female genital tract. Dysbiosis in both partners results in fertility problems, disorders in embryo implantation, or miscarriages. In addition, chronic inflammation of the male genitourinary system may accelerate the appearance of antisperm antibodies. A comprehensive examination of seminal microflora can clarify the causes of infertility or prevent pathological conditions that affect seminal parameters. Seminal microflora as a direct impact on fertility problems as well as a decrease in the effectiveness of assisted reproduction methods, insemination, or in vitro procedures.
引用
收藏
页数:8
相关论文
共 46 条
[1]   Improvement of semen parameters after antibiotic therapy in asymptomatic infertile men infected with Mycoplasma genitalium [J].
Ahmadi, Mohammad Hossein ;
Mirsalehian, Akbar ;
Gilani, Mohammad Ali Sadighi ;
Bahador, Abbas ;
Talebi, Malihe .
INFECTION, 2018, 46 (01) :31-38
[2]   The seminal microbiome in health and disease [J].
Altmae, Signe ;
Franasiak, Jason M. ;
Mandar, Reet .
NATURE REVIEWS UROLOGY, 2019, 16 (12) :703-721
[3]   Differential Composition of Vaginal Microbiome, but Not of Seminal Microbiome, Is Associated With Successful Intrauterine Insemination in Couples With Idiopathic Infertility: A Prospective Observational Study [J].
Amato, Virginia ;
Papaleo, Enrico ;
Pasciuta, Renee ;
Vigano, Paola ;
Ferrarese, Roberto ;
Clementi, Nicola ;
Sanchez, Ana Maria ;
Quaranta, Lavinia ;
Burioni, Roberto ;
Ambrosi, Alessandro ;
Salonia, Andrea ;
Clementi, Massimo ;
Candiani, Massimo ;
Mancini, Nicasio .
OPEN FORUM INFECTIOUS DISEASES, 2020, 7 (01)
[4]   Sperm Microbiota and Its Impact on Semen Parameters [J].
Baud, David ;
Pattaroni, Celine ;
Vulliemoz, Nicolas ;
Castella, Vincent ;
Marsland, Benjamin J. ;
Stojanov, Milos .
FRONTIERS IN MICROBIOLOGY, 2019, 10
[5]   Prevalence of sexually transmissible pathogens in semen from asymptomatic male infertility patients with and without leukocytospermia [J].
Bezold, Guntram ;
Politch, Joseph A. ;
Kiviat, Nancy B. ;
Kuypers, Jane M. ;
Wolff, Hans ;
Anderson, Deborah J. .
FERTILITY AND STERILITY, 2007, 87 (05) :1087-1097
[6]  
Bhatt C., 2015, INT J BIOMED RES, V6, P990, DOI [10.7439/ijbr, DOI 10.7439/IJBR]
[7]   Variations in Vaginal, Penile, and Oral Microbiota After Sexual Intercourse: A Case Report [J].
Carda-Dieguez, Miguel ;
Cardenas, Nivia ;
Aparicio, Marina ;
Beltran, David ;
Rodriguez, Juan M. ;
Mira, Alex .
FRONTIERS IN MEDICINE, 2019, 6
[8]   The microbiota continuum along the female reproductive tract and its relation to uterine-related diseases [J].
Chen, Chen ;
Song, Xiaolei ;
Wei, Weixia ;
Zhong, Huanzi ;
Dai, Juanjuan ;
Lan, Zhou ;
Li, Fei ;
Yu, Xinlei ;
Feng, Qiang ;
Wang, Zirong ;
Xie, Hailiang ;
Chen, Xiaomin ;
Zeng, Chunwei ;
Wen, Bo ;
Zeng, Liping ;
Du, Hui ;
Tang, Huiru ;
Xu, Changlu ;
Xia, Yan ;
Xia, Huihua ;
Yang, Huanming ;
Wang, Jian ;
Wang, Jun ;
Madsen, Lise ;
Brix, Susanne ;
Kristiansen, Karsten ;
Xu, Xun ;
Li, Junhua ;
Wu, Ruifang ;
Jia, Huijue .
NATURE COMMUNICATIONS, 2017, 8
[9]   Seminal bacterial composition in patients with obstructive and non-obstructive azoospermia [J].
Chen, Houyang ;
Luo, Tao ;
Chen, Tingtao ;
Wang, Gongxian .
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2018, 15 (03) :2884-2890
[10]   Genotypic diversity of clinical Actinomyces species:: Phenotype, source, and disease correlation among genospecies [J].
Clarridge, JE ;
Zhang, Q .
JOURNAL OF CLINICAL MICROBIOLOGY, 2002, 40 (09) :3442-3448