Urinary Retention Associated With Cariprazine: A Case Report

被引:2
作者
Kapulsky, Leonid [1 ]
Brody, Benjamin D. [1 ]
机构
[1] New York Presbyterian Hosp, Weill Cornell Med Ctr, 525 E 68th St, New York, NY 10065 USA
关键词
antipsychotic adverse effects; cariprazine; urinary retention;
D O I
10.1097/WNF.0000000000000301
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Urinary retention is a well-documented adverse effect of antipsychotic medications and is thought to be mediated by anticholinergic, adrenergic, and other neurotransmitter effects. Whereas urinary retention has been reported with typical and some atypical antipsychotics, there have been no reports of urinary retention with the novel antipsychotic cariprazine. We report on a case of urinary retention associated with cariprazine. Possible mechanisms for this adverse effect are discussed.
引用
收藏
页码:230 / 231
页数:2
相关论文
共 12 条
[1]   Micturition Difficulty Associated With Aripiprazole Report of 2 Cases [J].
Chiang, Chih-Lin ;
Liu, Chen-Chung .
JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 2011, 31 (01) :128-129
[2]   Long-term effects of cariprazine exposure on dopamine receptor subtypes [J].
Choi, Yong Kee ;
Adham, Nika ;
Kiss, Bela ;
Gyertyan, Istvan ;
Tarazi, Frank I. .
CNS SPECTRUMS, 2014, 19 (03) :268-277
[3]   Cariprazine: chemistry, pharmacodynamics, pharmacokinetics, and metabolism, clinical efficacy, safety, and tolerability [J].
Citrome, Leslie .
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, 2013, 9 (02) :193-206
[4]   Influence of central serotonergic mechanisms on lower urinary tract function [J].
de Groat, WC .
UROLOGY, 2002, 59 (5A) :30-36
[5]   Pharmacology of the lower urinary tract [J].
de Groat, WC ;
Yoshimura, N .
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 2001, 41 :691-721
[6]   Aripiprazole associated urine retention in a male schizophrenia patient [J].
Hsu, Wen-Yu ;
Chang, Ting-Gang ;
Chiu, Nan-Ying .
GENERAL HOSPITAL PSYCHIATRY, 2013, 35 (06) :680.e11-680.e12
[7]  
Kelly Christopher E, 2004, Rev Urol, V6 Suppl 1, pS32
[8]   Cariprazine (RGH-188), a Dopamine D3 Receptor-Preferring, D3/D2 Dopamine Receptor Antagonist-Partial Agonist Antipsychotic Candidate: In Vitro and Neurochemical Profile [J].
Kiss, Bela ;
Horvath, Attila ;
Nemethy, Zsolt ;
Schmidt, Eva ;
Laszlovszky, Istvan ;
Bugovics, Gyula ;
Fazekas, Karoly ;
Hornok, Katalin ;
Orosz, Szabolcs ;
Gyertyan, Istvan ;
Agai-Csongor, Eva ;
Domany, Gyoergy ;
Tihanyi, Karoly ;
Adham, Nika ;
Szombathelyi, Zsolt .
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2010, 333 (01) :328-340
[9]   A METHOD FOR ESTIMATING THE PROBABILITY OF ADVERSE DRUG-REACTIONS [J].
NARANJO, CA ;
BUSTO, U ;
SELLERS, EM ;
SANDOR, P ;
RUIZ, I ;
ROBERTS, EA ;
JANECEK, E ;
DOMECQ, C ;
GREENBLATT, DJ .
CLINICAL PHARMACOLOGY & THERAPEUTICS, 1981, 30 (02) :239-245
[10]  
Seki S, 2001, NEUROUROL URODYNAM, V20, P105, DOI 10.1002/1520-6777(2001)20:1<105::AID-NAU12>3.3.CO