Depressive symptomatology during clozapine treatment: two case reports

被引：2

作者：

Altamura, AC

Bignotti, S

Tura, G

Curreli, R

Pioli, R

机构：

[1] Univ Cagliari, Inst Psychiat, I-09127 Cagliari, Italy

[2] IREES, FBF, Inst Psychiat Rehabil S Cuore, Brescia, Italy

来源：

EUROPEAN NEUROPSYCHOPHARMACOLOGY | 1998年 / 8卷 / 03期

关键词：

schizophrenia; clozapine; depression; serotonergic drugs; paroxetine;

D O I：

10.1016/S0924-977X(97)00082-5

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We report the cases of two patients fulfilling DSM-IV criteria for schizophrenia, who developed a marked depressive symptomatology in the first period of a treatment with clozapine, and were treated successfully with serotonergic drugs (paroxetine, clomipramine). The AA. discuss the possible neurochemical determinants and implications of these clinical observations. (C) 1998 Elsevier Science B.V./ECNP.

引用

页码：239 / 240

页数：2