Regio and diastereoselective synthesis of functionalized 2,3-dihydrofuro[3,2-c]coumarins via a one-pot three-component reaction

被引：49

作者：

Altieri, Elisa ^{[1
]}

Cordaro, Massimiliano ^{[1
]}

Grassi, Giovanni ^{[1
]}

Risitano, Francesco ^{[1
]}

Scala, Angela ^{[1
]}

机构：

[1] Univ Messina, Dipartimento Chim Organ & Biol, I-98166 Messina, Italy

来源：

TETRAHEDRON | 2010年 / 66卷 / 49期

关键词：

Multicomponent reaction; Cyclization; Diastereoselectivity; 4; Hydroxycoumarin;

D O I：

10.1016/j.tet.2010.10.023

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient and straightforward synthesis of furo[3 2-c]coumarins via the one-pot three-component condensation of aromatic aldehydes 4-hydroxycoumarin and alpha-chloroketones in refluxing n-propanol is described Pyridine or a mixture of AcOH and AcONH4 was used as a basic catalyst (C) 2010 Elsevier Ltd All rights reserved

引用

页码：9493 / 9496

页数：4