Investigation of Salecan/poly(vinyl alcohol) hydrogels prepared by freeze/thaw method

被引：180
作者：
Qi, Xiaoliang [1 ]
Hu, Xinyu [1 ]
Wei, Wei [1 ]
Yu, Hao [1 ]
Li, Junjian [1 ]
Zhang, Jianfa [1 ]
Dong, Wei [1 ]
机构：
[1] Nanjing Univ Sci & Technol, Ctr Mol Metab, Nanjing 210094, Jiangsu, Peoples R China
来源：
CARBOHYDRATE POLYMERS | 2015年 / 118卷
基金：
中国国家自然科学基金;
关键词：
Salecan; Poly(vinyl alcohol); Freeze-thaw processing; Hybrid hydrogels; POLY VINYL ALCOHOL; SEMI-IPN HYDROGEL; POLY(VINYL ALCOHOL); POLYVINYL-ALCOHOL; COMPOSITE HYDROGELS; PORE STRUCTURE; DRUG-DELIVERY; PVA HYDROGELS; IN-VITRO; ALGINATE;
D O I：
10.1016/j.carbpol.2014.11.021
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Salecan is a novel water-soluble extracellular-glucan produced by a new kind of salt-tolerant strain Agrobacterium sp. ZX09 and can be applied in food and medicine industries. In this work, Salecan (Sal) was incorporated into poly(vinyl alcohol) (PVA) to prepare novel Sal/PVA hybrid hydrogels by repeated freeze-thaw processing. Physicochemical and biological characteristics of the hydrogels were investigated to evaluate their potential as cell adhesion materials. By increasing the Salecan content in the hybrid hydrogels, their swelling capacity increased notably, while the compressive modulus decreased. Observed by SEM, Sal/PVA hydrogels had a homogeneous porous structure. The degradation rate of the hydrogels can be controlled by tailoring the composition ratio of Sal/PVA. Furthermore, cells could adhere well on the surface of Sal/PVA hydrogels. In conclusion, these results make Sal/PVA hydrogels attractive materials for biomedical applications. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码：60 / 69
页数：10
相关论文
共 58 条
[1]   Biosynthetic hydrogel scaffolds made from fibrinogen and polyethylene glycol for 3D cell cultures [J].
Almany, L ;
Seliktar, D .
BIOMATERIALS, 2005, 26 (15) :2467-2477
[2]   Poly(Vinyl Alcohol) Physical Hydrogels: New Vista on a Long Serving Biomaterial [J].
Alves, Marie-Helene ;
Jensen, Bettina E. B. ;
Smith, Anton A. A. ;
Zelikin, Alexander N. .
MACROMOLECULAR BIOSCIENCE, 2011, 11 (10) :1293-1313
[3]   Removal of Paraquat Pesticide from Aqueous Solutions Using a Novel Adsorbent Material Based on Polyacrylamide and Methylcellulose Hydrogels [J].
Aouada, Fauze A. ;
Pan, Zhongli ;
Orts, William J. ;
Mattoso, Luiz H. C. .
JOURNAL OF APPLIED POLYMER SCIENCE, 2009, 114 (04) :2139-2148
[4]   Preparation and Characterization of Hydrophilic, Spectroscopic, and Kinetic Properties of Hydrogels Based on Polyacrylamide and Methylcellulose Polysaccharide [J].
Aouada, Fauze Ahmad ;
de Moura, Marcia Regina ;
Lopes da Silva, Wilson Tadeu ;
Muniz, Edvani Curti ;
Capparelli Mattoso, Luiz Henrique .
JOURNAL OF APPLIED POLYMER SCIENCE, 2011, 120 (05) :3004-3013
[5]   Fabrication of porous polysaccharide-based scaffolds using a combined freeze-drying/cross-linking process [J].
Autissier, Aude ;
Le Visage, Catherine ;
Pouzet, Cecile ;
Chaubet, Frederic ;
Letourneur, Didier .
ACTA BIOMATERIALIA, 2010, 6 (09) :3640-3648
[6]   A pH-sensitive graphene oxide composite hydrogel [J].
Bai, Hua ;
Li, Chun ;
Wang, Xiaolin ;
Shi, Gaoquan .
CHEMICAL COMMUNICATIONS, 2010, 46 (14) :2376-2378
[7]   Evaluation of an in situ forming hydrogel wound dressing based on oxidized alginate and gelatin [J].
Balakrishnan, B ;
Mohanty, M ;
Umashankar, PR ;
Jayakrishnan, A .
BIOMATERIALS, 2005, 26 (32) :6335-6342
[8]   Application of Polysaccharide Hydrogels in Adsorption and Controlled-Extended Release of Fertilizers Processes [J].
Bortolin, Adriel ;
Aouada, Fauze A. ;
de Moura, Marcia R. ;
Ribeiro, Caue ;
Longo, Elson ;
Mattoso, Luiz H. C. .
JOURNAL OF APPLIED POLYMER SCIENCE, 2012, 123 (04) :2291-2298
[9]   NERVE-FIBER GROWTH ON DEFINED HYDROGEL SUBSTRATES [J].
CARBONETTO, ST ;
GRUVER, MM ;
TURNER, DC .
SCIENCE, 1982, 216 (4548) :897-899
[10]   Effect of chitosan and dextran on the properties of poly(vinyl alcohol) hydrogels [J].
Cascone, MG ;
Maltinti, S ;
Barbani, N ;
Laus, M .
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 1999, 10 (07) :431-435
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