Long-term biological effects in sickle cell disease: insights from a post-crizanlizumab study

被引：5

作者：

Liles, Darla K. ^{[1
]}

Shah, Nirmish R. ^{[2
]}

Scullin, Brigid ^{[3
]}

Gordeuk, Victor R. ^{[4
]}

Smith, Wally R. ^{[5
]}

Kanter, Julie ^{[6
]}

Achebe, Maureen M. ^{[7
]}

Boccia, Ralph ^{[8
]}

Crary, Shelley E. ^{[9
]}

Kraft, Walter K. ^{[10
]}

Archer, Natasha ^{[11
]}

Cataldo, Vince ^{[12
]}

Hardesty, Brandon M. ^{[13
]}

Idowu, Modupe ^{[14
]}

Desai, Payal C. ^{[15
]}

Ikeda, Alan ^{[16
]}

Puthenveetil, Geetha ^{[17
]}

Hassell, Kathryn L. ^{[18
]}

Sarnaik, Sharada ^{[19
]}

Kutlar, Abdullah ^{[20
]}

机构：

[1] East Carolina Univ, Brody Sch Med, Greenville, NC 27858 USA

[2] Duke Univ, Med Ctr, Durham, NC USA

[3] Univ North Carolina Hlth Care, Chapel Hill, NC USA

[4] Univ Illinois, Chicago, IL USA

[5] Virginia Commonwealth Univ, Richmond, VA USA

[6] Univ Alabama Birmingham, Birmingham, AL USA

[7] Brigham & Womens Hosp, 75 Francis St, Boston, MA 02115 USA

[8] Ctr Canc & Blood Disorders, Bethesda, MD USA

[9] Univ Arkansas Med Sci, Little Rock, AR 72205 USA

[10] Thomas Jefferson Univ, Philadelphia, PA 19107 USA

[11] Dana Farber Boston Childrens Canc & Blood Disorde, Boston, MA USA

[12] Our Lady Lake Mary Bird Perkins Canc Ctr, Baton Rouge, LA USA

[13] Indiana Hemophilia & Thrombosis Ctr, Indianapolis, IN USA

[14] Univ Texas Hlth Sci Ctr Houston, Houston, TX 77030 USA

[15] Ohio State Univ, Wexner Med Ctr, Columbus, OH 43210 USA

[16] Childrens Specialty Ctr Nevada, Las Vegas, NV USA

[17] Childrens Hosp Orange Cty, Orange, CA 92668 USA

[18] Univ Colorado, Sch Med, Denver, CO USA

[19] Childrens Hosp Michigan, Detroit, MI 48201 USA

[20] Med Coll Georgia, Sickle Cell Ctr, Augusta, GA 30912 USA

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 2021年 / 195卷 / 04期

关键词：

crizanlizumab; monoclonal antibody; sickle cell disease; vaso-occlusive crisis; P-SELECTIN; ADHESION;

D O I：

10.1111/bjh.17739

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：E150 / E153

页数：4

共 11 条

[1] Crizanlizumab for the Prevention of Pain Crises in Sickle Cell Disease [J].

Ataga, K. I. ;

Kutlar, A. ;

Kanter, J. ;

Liles, D. ;

Cancado, R. ;

Friedrisch, J. ;

Guthrie, T. H. ;

Knight-Madden, J. ;

Alvarez, O. A. ;

Gordeuk, V. R. ;

Gualandro, S. ;

Colella, M. P. ;

Smith, W. R. ;

Rollins, S. A. ;

Stocker, J. W. ;

Rother, R. P. .

NEW ENGLAND JOURNAL OF MEDICINE, 2017, 376 (05) :429-439

[2] Critical role of endothelial cell activation in hypoxia-induced vasoocclusion in transgenic sickle mice [J].

Belcher, JD ;

Mahaseth, H ;

Welch, TE ;

Vilback, AE ;

Sonbol, KM ;

Kalambur, VS ;

Bowlin, PR ;

Bischof, JC ;

Hebbel, RP ;

Vercellotti, GM .

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2005, 288 (06) :H2715-H2725

[3] Acute Care Utilization and Rehospitalizations for Sickle Cell Disease [J].

Brousseau, David C. ;

Owens, Pamela L. ;

Mosso, Andrew L. ;

Panepinto, Julie A. ;

Steiner, Claudia A. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2010, 303 (13) :1288-1294

[4] Inhibition of cell adhesion by anti-P-selectin aptamer: a new potential therapeutic agent for sickle cell disease [J].

Gutsaeva, Diana R. ;

Parkerson, James B. ;

Yerigenahally, Shobha D. ;

Kurz, Jeffrey C. ;

Schaub, Robert G. ;

Ikuta, Tohru ;

Head, C. Alvin .

BLOOD, 2011, 117 (02) :727-735

[5] Roles of P-selectin in inflammation, neointimal formation, and vascular remodeling in balloon-injured rat carotid arteries [J].

Hayashi, S ;

Watanabe, N ;

Nakazawa, K ;

Suzuki, J ;

Tsushima, K ;

Tamatani, T ;

Sakamoto, S ;

Isobe, M .

CIRCULATION, 2000, 102 (14) :1710-1717

[6]

Loeffler P, 2015, BLOOD, V126

[7] Leukocyte adhesion and the pathophysiology of sickle cell disease [J].

Okpala, H .

CURRENT OPINION IN HEMATOLOGY, 2006, 13 (01) :40-44

[8] Sickle Cell Disease [J].

Piel, Frederic B. ;

Steinberg, Martin H. ;

Rees, David C. .

NEW ENGLAND JOURNAL OF MEDICINE, 2017, 376 (16) :1561-1573

[9] Sickle-cell disease [J].

Rees, David C. ;

Williams, Thomas N. ;

Gladwin, Mark T. .

LANCET, 2010, 376 (9757) :2018-2031

[10] Predicting clinical severity in sickle cell anaemia [J].

Steinberg, MH .

BRITISH JOURNAL OF HAEMATOLOGY, 2005, 129 (04) :465-481

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