Imidazo[1,2-a]pyridine as a promising scaffold for the development of antibacterial agents

被引:16
作者
Mishra, Nilima Priyadarsini [1 ]
Mohapatra, Seetaram [1 ]
Das, Tapaswini [1 ]
Nayak, Sabita [1 ]
机构
[1] Ravenshaw Univ, Dept Chem, Cuttack, India
关键词
BIOLOGICAL EVALUATION; ANTIBIOTIC-RESISTANCE; ANTIMICROBIAL EVALUATION; DNA GYRASE; DERIVATIVES; POTENT; ZOLPIDEM; DESIGN; DISCOVERY; FUNCTIONALIZATION;
D O I
10.1002/jhet.4534
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The fascinating molecular structure and versatile bioactivity of imidazo[1,2-a]pyridine scaffold attracts the scientific community to develop new imidazo[1,2-a]pyridine based antibacterial agent in current situation. This systematic review provides a deep insight into the recent advances of imidazo[1,2-a]pyridine derivatives and its antibacterial activities from 2010 to 2021. Moreover, the structure-activity relationship and synthetic approaches are also cautiously summarized throughout the review which affords a clear vision for the medicinal chemists to design new antibacterial agents.
引用
收藏
页码:2051 / 2075
页数:25
相关论文
共 111 条
[91]   Coumarin derivatives as promising antibacterial agent(s) [J].
Sahoo, Chita Ranjan ;
Sahoo, Jyotirmaya ;
Mahapatra, Monalisa ;
Lenka, Debananda ;
Sahu, Pratap Kumar ;
Dehury, Budheswar ;
Padhy, Rabindra Nath ;
Paidesetty, Sudhir Kumar .
ARABIAN JOURNAL OF CHEMISTRY, 2021, 14 (02)
[92]   Synthesis of functionalized dihydroimidazo[1,2-A]pyridines and 4-thiazolidinone derivatives from maleimide, as new class of antimicrobial agents [J].
Salhi, Lydia ;
Achouche-Bouzroura, Samia ;
Nechak, Rosa ;
Nedjar-Kolli, Bellara ;
Rabia, Cherifa ;
Merazig, Hocine ;
Poulain-Martini, Sophie ;
Dunach, Elisabet .
SYNTHETIC COMMUNICATIONS, 2020, 50 (03) :412-422
[93]   Fe(iii)-Catalyzed synthesis of steroidal imidazoheterocycles as potent antiproliferative agents [J].
Samanta, Sadhanendu ;
Ghosh, Asim Kumar ;
Ghosh, Sumit ;
Ilina, Anastasia A. ;
Volkova, Yulia A. ;
Zavarzin, Igor, V ;
Scherbakov, Alexander M. ;
Salnikova, Diana, I ;
Dzichenka, Yaraslau U. ;
Sachenko, Anton B. ;
Shirinian, Valerii Z. ;
Hajra, Alakananda .
ORGANIC & BIOMOLECULAR CHEMISTRY, 2020, 18 (29) :5571-5576
[94]   Design, synthesis, and pharmacology of some oxadiazole and hydroxypyrazoline hybrids bearing thiazoyl scaffold: antiproliferative activity, molecular docking and DNA binding studies [J].
Santosh, Rangappa ;
Prabhu, Ashwini ;
Selvam, Mukunthan K. ;
Krishna, Panchangam M. ;
Nagaraja, Gundibasappa K. ;
Rekha, Punchappady D. .
HELIYON, 2019, 5 (02)
[95]   Design, synthesis and in vitro evaluation of coumarin-imidazo[1,2-a]pyridine derivatives against cancer induced osteoporosis [J].
Sashidhara, Koneni V. ;
Singh, L. Ravithej ;
Choudhary, Dharmendra ;
Arun, Ashutosh ;
Gupta, Sampa ;
Adhikary, Sulekha ;
Palnati, Gopala Reddy ;
Konwar, Rituraj ;
Trivedi, Ritu .
RSC ADVANCES, 2016, 6 (83) :80037-80048
[96]   The multifaceted roles of antibiotics and antibiotic resistance in nature [J].
Sengupta, Saswati ;
Chattopadhyay, Madhab K. ;
Grossart, Hans-Peter .
FRONTIERS IN MICROBIOLOGY, 2013, 4
[97]   Synthesis and biological activities of some fused pyran derivatives [J].
Shehab, Wesam S. ;
Ghoneim, Amira A. .
ARABIAN JOURNAL OF CHEMISTRY, 2016, 9 :S966-S970
[98]   Synthesis and Biological Activity of Thiazolyl-Acetic Acid Derivatives as Possible Antimicrobial Agents [J].
Shirai, Akihiro ;
Fumoto, Yasuko ;
Shouno, Tomoaki ;
Maseda, Hideaki ;
Omasa, Takeshi .
BIOCONTROL SCIENCE, 2013, 18 (02) :59-73
[99]   Challenges of Antibacterial Discovery [J].
Silver, Lynn L. .
CLINICAL MICROBIOLOGY REVIEWS, 2011, 24 (01) :71-+
[100]   Synthesis, cytotoxicity, pharmacokinetic profile, binding with DNA and BSA of new imidazo[1,2-a]pyrazine-benzo[d]imidazol-5-yl hybrids [J].
Singh, Iqubal ;
Luxami, Vijay ;
Paul, Kamaldeep .
SCIENTIFIC REPORTS, 2020, 10 (01)