tRNA biology charges to the front

被引：621

作者：

Phizicky, Eric M. ^{[1
]}

Hopper, Anita K. ^{[2
]}

机构：

[1] Univ Rochester, Sch Med, Ctr RNA Biol, Dept Biochem & Biophys, Rochester, NY 14642 USA

[2] Ohio State Univ, Dept Mol Genet, Ctr RNA Biol, Columbus, OH 43210 USA

来源：

GENES & DEVELOPMENT | 2010年 / 24卷 / 17期

关键词：

Cleavage; modifications; processing; splicing; tRNA; trafficking; turnover; YEAST TRANSFER-RNA; POLYMERASE-III TRANSCRIPTION; MITOCHONDRIAL TRANSFER-RNA; CYTOPLASMIC TRANSFER-RNAS; PRECURSOR TRANSFER-RNAS; SACCHAROMYCES-CEREVISIAE TRNA(HIS); 3' PROCESSING ENDORIBONUCLEASE; KLUYVEROMYCES-LACTIS ZYMOCIN; PHENYLALANINE TRANSFER-RNA; HISTIDINE TRANSFER-RNA;

D O I：

10.1101/gad.1956510

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

tRNA biology has come of age, revealing an unprecedented level of understanding and many unexpected discoveries along the way. This review highlights new findings on the diverse pathways of tRNA maturation, and on the formation and function of a number of modifications. Topics of special focus include the regulation of tRNA biosynthesis, quality control tRNA turnover mechanisms, widespread tRNA cleavage pathways activated in response to stress and other growth conditions, emerging evidence of signaling pathways involving tRNA and cleavage fragments, and the sophisticated intracellular tRNA trafficking that occurs during and after biosynthesis.

引用

页码：1832 / 1860

页数：29

共 379 条

[21] Trm9-catalyzed tRNA modifications link translation to the DNA damage response [J].

Begley, Ulrike ;

Dyavaiah, Madhu ;

Patil, Ashish ;

Rooney, John P. ;

DiRenzo, Dan ;

Young, Christine M. ;

Conklin, Douglas S. ;

Zitomer, Richard S. ;

Begley, Thomas J. .

MOLECULAR CELL, 2007, 28 (05) :860-870

[22] Pseudouridylation at position 32 of mitochondrial and cytoplasmic tRNAs requires two distinct enzymes in Saccharomyces cerevisiae [J].

Behm-Ansmant, I ;

Grosjean, H ;

Massenet, S ;

Motorin, Y ;

Branlant, C .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (51) :52998-53006

[23] The Saccharomyces cerevisiae U2 snRNA:pseudouridine-synthase Pus7p is a novel multisite-multisubstrate RNA:Ψ-synthase also acting on tRNAs [J].

Behm-Ansmant, I ;

Urban, A ;

Ma, XJ ;

Yu, YT ;

Motorin, Y ;

Branlant, C .

RNA, 2003, 9 (11) :1371-1382

[24] The Saccharomyces cerevisiae Pus2 protein encoded by YGL063w ORF is a mitochondrial tRNA:: Ψ27/28-synthase [J].

Behm-Ansmant, Isabelle ;

Branlant, Christiane ;

Motorin, Yuri .

RNA, 2007, 13 (10) :1641-1647

[25] Nucleolar localization of early tRNA processing [J].

Bertrand, E ;

Houser-Scott, F ;

Kendall, A ;

Singer, RH ;

Engelke, DR .

GENES & DEVELOPMENT, 1998, 12 (16) :2463-2468

[26] Identification of the tRNA-dihydrouridine synthase family [J].

Bishop, AC ;

Xu, JM ;

Johnson, RC ;

Schimmel, P ;

de Crécy-Lagard, V .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (28) :25090-25095

[27] A conserved modified wobble nucleoside (mcm5s2U) in lysyl-tRNA is required for viability in yeast [J].

Bjork, Glenn R. ;

Huang, Bo ;

Persson, Olof P. ;

Bystrom, Anders S. .

RNA, 2007, 13 (08) :1245-1255

[28] A primordial tRNA modification required for the evolution of life? [J].

Björk, GR ;

Jacobsson, K ;

Nilsson, K ;

Johansson, MJO ;

Byström, AS ;

Persson, OP .

EMBO JOURNAL, 2001, 20 (1-2) :231-239

[29] Control of RNA polymerases I and III by the TOR signaling pathway [J].

Boguta, Magdalena .

CELL CYCLE, 2009, 8 (24) :4023-4024

[30] Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm [J].

Bohnsack, MT ;

Regener, K ;

Schwappach, B ;

Saffrich, R ;

Paraskeva, E ;

Hartmann, E ;

Görlich, D .

EMBO JOURNAL, 2002, 21 (22) :6205-6215

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