Exploring the in Vivo Mechanisms of Action of Glucokinase Activators in Type 2 Diabetes

被引：14
|
作者：
Perseghin, Gianluca [1 ,2 ]
机构：
[1] Ist Sci H San Raffaele, Div Metab & Cardiovasc Sci, I-20132 Milan, Italy
[2] Univ Milan, Dept Sport Sci Nutr & Hlth, I-20129 Milan, Italy
来源：
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM | 2010年 / 95卷 / 11期
关键词：
THERAPY; GENE;
D O I：
10.1210/jc.2010-2049
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：4871 / 4873
页数：3
相关论文
共 50 条
  • [1] Glucokinase activators for the treatment of type 2 diabetes
    Johnson, Theodore O.
    Humphries, Paul S.
    ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 41, 2006, 41 : 141 - 154
  • [2] Glucokinase Activators for the Potential Treatment of Type 2 Diabetes
    Grimsby, J.
    Berthel, S. J.
    Sarabu, R.
    CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2008, 8 (17) : 1524 - 1532
  • [3] New hope for glucokinase activators in type 2 diabetes?
    Scheen, Andre J.
    LANCET DIABETES & ENDOCRINOLOGY, 2018, 6 (08): : 591 - 593
  • [4] Glucokinase Activators for Type 2 Diabetes: Challenges and Future Developments
    Konstantinos A. Toulis
    Krishnarajah Nirantharakumar
    Chrysa Pourzitaki
    Anthony H. Barnett
    Abd A. Tahrani
    Drugs, 2020, 80 : 467 - 475
  • [5] Recent advances in glucokinase activators for the treatment of type 2 diabetes
    Pal, Manojit
    DRUG DISCOVERY TODAY, 2009, 14 (15-16) : 784 - 792
  • [6] Glucokinase Activators for Type 2 Diabetes: Challenges and Future Developments
    Toulis, Konstantinos A.
    Nirantharakumar, Krishnarajah
    Pourzitaki, Chrysa
    Barnett, Anthony H.
    Tahrani, Abd A.
    DRUGS, 2020, 80 (05) : 467 - 475
  • [7] Glucokinase activators as new type 2 diabetes therapeutic agents
    Sarabu, Ramakanth
    Berthel, Steven J.
    Kester, Robert F.
    Tilley, Jefferson W.
    EXPERT OPINION ON THERAPEUTIC PATENTS, 2008, 18 (07) : 759 - 768
  • [8] Targeting human Glucokinase for the treatment of type 2 diabetes: an overview of allosteric Glucokinase activators
    Sharma, Prateek
    Singh, Sukhbir
    Sharma, Neelam
    Singla, Deepak
    Guarve, Kumar
    Grewal, Ajmer Singh
    JOURNAL OF DIABETES AND METABOLIC DISORDERS, 2022, 21 (01) : 1129 - 1137
  • [9] Targeting human Glucokinase for the treatment of type 2 diabetes: an overview of allosteric Glucokinase activators
    Prateek Sharma
    Sukhbir Singh
    Neelam Sharma
    Deepak Singla
    Kumar Guarve
    Ajmer Singh Grewal
    Journal of Diabetes & Metabolic Disorders, 2022, 21 : 1129 - 1137
  • [10] Strategies for the design of hepatoselective glucokinase activators to treat type 2 diabetes
    Pfefferkorn, Jeffrey A.
    EXPERT OPINION ON DRUG DISCOVERY, 2013, 8 (03) : 319 - 330
12345