A neurodevelopmental model for anorexia nervosa

被引：166

作者：

Connan, F

Campbell, IC

Katzman, M

Lightman, SL

Treasure, J

机构：

[1] Bristol Royal Infirm & Gen Hosp, Dept Med, Bristol BS2 8HW, Avon, England

[2] Weill Cornell Med Ctr, New York, NY USA

[3] Inst Psychiat, Dept Psychol, London SE5 8AF, England

[4] Kings Coll London, Inst Psychiat, London SE5 8PF, England

来源：

PHYSIOLOGY & BEHAVIOR | 2003年 / 79卷 / 01期

关键词：

anorexia nervosa; aetiology; developmental; attachment; HPA axis; chronic stress;

D O I：

10.1016/S0031-9384(03)00101-X

中图分类号：

B84 [心理学];

学科分类号：

04 ; 0402 ;

摘要：

This paper integrates genetic and biological data on aetiological risk for anorexia nervosa (AN) with cognitive and psychosocial explanatory models. We have reviewed clinical and basic science data from each of these domains and then used a developmental perspective to formulate a multifactorial threshold model. By positioning interpersonal stress as a central component of this model, psychological, social and biological conceptualisations of AN can be used to generate a data driven, neurodevelopmental hypothesis for the aetiology of this complex disorder. (C) 2003 Elsevier Science Inc. All rights reserved.

引用

页码：13 / 24

页数：12

共 155 条

[1] Vasopressinergic regulation of the hypothalamic-pituitary-adrenal axis: implications for stress adaptation [J].