The effects of ginseng on the metabolic syndrome: An updated review

被引:27
作者
Aminifard, Tahereh [1 ]
Razavi, Bibi Marjan [1 ,2 ]
Hosseinzadeh, Hossein [1 ,3 ]
机构
[1] Mashhad Univ Med Sci, Sch Pharm, Dept Pharmacodynam & Toxicol, Mashhad, Razavi Khorasan, Iran
[2] Mashhad Univ Med Sci, Targeted Drug Delivery Res Ctr, Pharmaceut Technol Inst, Mashhad, Razavi Khorasan, Iran
[3] Mashhad Univ Med Sci, Pharmaceut Res Ctr, Pharmaceut Technol Inst, Mashhad, Razavi Khorasan, Iran
关键词
diabetes; ginseng; herbal medicine; hypertension; metabolic syndrome; Panax ginseng; HIGH-FAT DIET; KOREAN RED GINSENG; PANAX-QUINQUEFOLIUS L; IMPROVES LIPID-METABOLISM; INSULIN-RESISTANCE; BLOOD-PRESSURE; FERMENTED GINSENG; ARTERIAL STIFFNESS; HIGH-CHOLESTEROL; PPAR-GAMMA;
D O I
10.1002/fsn3.2475
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Metabolic syndrome is a group of risk factors including high blood glucose, dyslipidemia, high blood pressure, and high body weight. It can increase the risk of diabetes and cardiovascular disorders, which are the important reasons for death around the world. Nowadays, there are numerous demands for herbal medicine because of less harmful effects and more useful effects in comparison with chemical options. Ginseng is one of the most famous herbs used as a drug for a variety of disorders in humans. The antihyperlipidemia, antihypertension, antihyperglycemic, and anti-obesity effects of ginseng and its active constituents such as ginsenosides have been shown in different studies. In this review article, the different in vitro, in vivo, and human studies concerning the effects of ginseng and its active constituents in metabolic syndrome have been summarized. According to these studies, ginseng can control metabolic syndrome and related diseases.
引用
收藏
页码:5293 / 5311
页数:19
相关论文
共 146 条
[11]  
Christensen LP, 2009, ADV FOOD NUTR RES, V55, P1, DOI 10.1016/S1043-4526(08)00401-4
[12]   Aged ginseng (Panax ginseng Meyer) reduces blood glucose levels and improves lipid metabolism in high fat diet-fed mice [J].
Chung, Soo Im ;
Nam, Su Jin ;
Xu, Mingze ;
Kang, Mi Young ;
Lee, Sang Chul .
FOOD SCIENCE AND BIOTECHNOLOGY, 2016, 25 (01) :267-273
[13]   Comparative Study on the Hypoglycemic and Antioxidative Effects of Fermented Paste (Doenjang) Prepared from Soybean and Brown Rice Mixed with Rice Bran or Red Ginseng Marc in Mice Fed with High Fat Diet [J].
Chung, Soo Im ;
Rico, Catherine W. ;
Kang, Mi Young .
NUTRIENTS, 2014, 6 (10) :4610-4624
[14]   Engineered Silybin Nanoparticles Educe Efficient Control in Experimental Diabetes [J].
Das, Suvadra ;
Roy, Partha ;
Pal, Rajat ;
Auddy, Runa Ghosh ;
Chakraborti, Abhay Sankar ;
Mukherjee, Arup .
PLOS ONE, 2014, 9 (07)
[15]  
Dehghani S, 2019, IRAN J BASIC MED SCI, V22, P460, DOI 10.22038/IJBMS.2019.31964.7678
[16]   The effects of Ginkgo biloba on metabolic syndrome: A review [J].
Eisvand, Farhad ;
Razavi, Bibi Marjan ;
Hosseinzadeh, Hossein .
PHYTOTHERAPY RESEARCH, 2020, 34 (08) :1798-1811
[17]  
El Arab AE, 2016, ARAB J NUCL SCI APPL, V49, P237
[18]  
El-Khayat Z, 2011, J MED PLANTS RES, V5, P4616
[19]   Ginsenoside Rg1 attenuates hepatic insulin resistance induced by high-fat and high-sugar by inhibiting inflammation [J].
Fan, Xiaoming ;
Zhang, Chao ;
Niu, Shiwei ;
Fan, Biao ;
Gu, Danshan ;
Jiang, Kerong ;
Li, Ruonan ;
Li, Shude .
EUROPEAN JOURNAL OF PHARMACOLOGY, 2019, 854 :247-255
[20]   Investigations on the effects of ginsenoside-Rg1 on glucose uptake and metabolism in insulin resistant HepG2 cells [J].
Fan, Xiaoming ;
Tao, Junyan ;
Zhou, Yulin ;
Hou, Yunhe ;
Wang, Yiyu ;
Gu, Danshan ;
Su, Yanmei ;
Jang, Yanping ;
Li, Shude .
EUROPEAN JOURNAL OF PHARMACOLOGY, 2019, 843 :277-284