Tissue microarrays in clinical urology - Technical considerations

被引：12
作者：
Kramer, Mario W. [1 ]
Merseburger, Axel S. [1 ]
Hennenlotter, Jorg [1 ]
Kuczyk, Markus [1 ]
机构：
[1] Univ Tubingen, Dept Urol, D-72076 Tubingen, Germany
来源：
SCANDINAVIAN JOURNAL OF UROLOGY AND NEPHROLOGY | 2007年 / 41卷 / 06期
关键词：
tissue microarray; technical considerations; advantages; disadvantages; manual application;
D O I：
10.1080/00365590701430737
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
The tissue microarray (TMA) technique is a 'high-throughput' tool which enables a rapid and concurrent analysis of molecular targets in large numbers of specimens at the DNA, RNA and protein levels under standardized conditions. In addition, TMA is a cost-and time-efficient method. This review focuses on its technical side, outlining its advantages and weaknesses. It also gives an overview of some major studies of bladder and prostate cancer in which the TMA technique was used.
引用
收藏
页码：478 / 484
页数：7
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