Telomeres, Aging, and Plants: From Weeds to Methuselah - A Mini-Review

被引：47
作者：
Watson, J. Mathew [1 ]
Riha, Karel [1 ]
机构：
[1] Austrian Acad Sci, Gregor Mendel Inst Mol Plant Biol, AT-1030 Vienna, Austria
来源：
GERONTOLOGY | 2011年 / 57卷 / 02期
基金：
奥地利科学基金会;
关键词：
DNA repair; Leaf senescence; Meristem; Perennials; Plants; Seed longevity; Telomerase; Telomeres; LIFE-SPAN; REVERSE-TRANSCRIPTASE; CELLULAR SENESCENCE; LEAF SENESCENCE; CALLUS-CULTURE; DNA-DAMAGE; AGE; ARABIDOPSIS; CELLS; TREES;
D O I：
10.1159/000310174
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
The process of aging affects most, if not all, living creatures, from single celled yeast to multi-cellular mammals and plants. The DNA end-replication problem along with the tissue-limited expression of telomerase led to the telomere hypothesis of aging, where limits on cellular proliferation are genetically encoded in the lengths of a cell's telomeres. Support for this hypothesis has been found in several organisms, from worms to mice to humans. While development, and therefore the process of aging, is quite different between plants and animals, telomere biology between these organisms is fundamentally the same. Do telomeres, then, also play the role of a molecular clock in plants? In this review, we explore the current knowledge of the relationship between telomeres and aging in plants in three specific cases: leaf senescence, aging of perennials and seed longevity. Copyright (C) 2010 S. Karger AG, Basel
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页码：129 / 136
页数：8
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