Synthesis of piperazinones and benzopiperazinones from 1,2-diamines and organoboronic acids

被引：75

作者：

Petasis, NA ^{[1
]}

Patel, ZD

机构：

[1] Univ So Calif, Dept Chem, Los Angeles, CA 90089 USA

[2] Univ So Calif, Loker Hydrocarbon Res Inst, Los Angeles, CA 90089 USA

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 49期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4039(00)01717-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Alkenyl, aryl and heteroaryl boronic acids react with 1,2-diamines and glyoxylic acid to give directly in one step the corresponding piperazinones (2-oxopiperazines). Similarly, the use of monoprotected 1,2-phenylenediamine leads to benzopiperazinones( 1,2,3,4-tetrahydroquinoxalin-2-ones). (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：9607 / 9611

页数：5

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