Non-covalent phosphorylcholine coating reduces protein adsorption and phagocytic uptake of microparticles

被引：7
|
作者：
Garapaty, Anusha [1 ]
Champion, Julie A. [1 ]
机构：
[1] Georgia Inst Technol, Sch Chem & Biomol Engn, Atlanta, GA 30332 USA
来源：
CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 72期
关键词：
SELF-ASSEMBLED MONOLAYERS; POLYMER NANOPARTICLES; OXIDE NANOPARTICLES; STRONG RESISTANCE; SURFACE-CHARGE; SERUM-PROTEINS; CELLS; PEG; ACTIVATION; ADHESION;
D O I：
10.1039/c5cc03459k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Phosphorylcholine co-polymer was assembled on model polystyrene microparticles through a simple, widely-applicable ethanol coating process. The coating rendered particles resistant to protein adsorption and phagocytosis by macrophages, making it useful for a range of biological applications.
引用
收藏
页码：13814 / 13817
页数：4
相关论文
共 50 条
  • [41] Visualization and analysis of non-covalent contacts using the Protein Contacts Atlas
    Melis Kayikci
    A. J. Venkatakrishnan
    James Scott-Brown
    Charles N. J. Ravarani
    Tilman Flock
    M. Madan Babu
    Nature Structural & Molecular Biology, 2018, 25 : 185 - 194
  • [42] The role of non-covalent protein binding in skin sensitisation potency of chemicals
    Aleksic, Maja
    Thain, Emma
    Gutsell, Stephen J.
    Pease, Camilla K.
    Basketter, David A.
    CUTANEOUS AND OCULAR TOXICOLOGY, 2007, 26 (02) : 161 - 169
  • [43] Non-Covalent Carrier Hydrophobicity as a Universal Predictor of Intracellular Protein Activity
    Hango, Christopher R.
    Backlund, Coralie M.
    Davis, Hazel C.
    Posey, Nicholas D.
    Minter, Lisa M.
    Tew, Gregory N.
    BIOMACROMOLECULES, 2021, 22 (07) : 2850 - 2863
  • [44] Non-covalent protein-polysaccharide interactions and their influence on membrane fouling
    Neemann, F.
    Rosenberger, S.
    Jefferson, B.
    McAdam, E. J.
    JOURNAL OF MEMBRANE SCIENCE, 2013, 446 : 310 - 317
  • [45] Hydrochar as protein support: preservation of biomolecule properties with non-covalent immobilization
    Castro, Manuela Oliveira
    de Santiago, Mayara Queiroz
    Nascimento, Kyria Santiago
    Cavada, Benildo Sousa
    Miguel, Emilio de Castro
    de Paula, Amauri Jardim
    Ferreira, Odair Pastor
    JOURNAL OF MATERIALS SCIENCE, 2017, 52 (23) : 13378 - 13389
  • [46] Hydrochar as protein support: preservation of biomolecule properties with non-covalent immobilization
    Manuela Oliveira Castro
    Mayara Queiroz de Santiago
    Kyria Santiago Nascimento
    Benildo Sousa Cavada
    Emilio de Castro Miguel
    Amauri Jardim de Paula
    Odair Pastor Ferreira
    Journal of Materials Science, 2017, 52 : 13378 - 13389
  • [47] Visualization and analysis of non-covalent contacts using the Protein Contacts Atlas
    Kayikci, Melis
    Venkatakrishnan, A. J.
    Scott-Brown, James
    Ravarani, Charles N. J.
    Flock, Tilman
    Babu, M. Madan
    NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2018, 25 (02) : 185 - +
  • [48] The effect of non-covalent interactions of xylitol with whey protein and casein on structure and functionality of protein
    Kong, Fanhua
    Kang, Shimo
    An, Yuejia
    Li, Weixuan
    Han, Hongjiao
    Guan, Boyuan
    Yang, Mei
    Zheng, Yan
    Yue, Xiqing
    INTERNATIONAL DAIRY JOURNAL, 2020, 111
  • [49] Non-covalent interaction of soy protein isolate and catechin: Mechanism and effects on protein conformation
    Dai, Shicheng
    Lian, Ziteng
    Qi, Weijie
    Chen, Yashuang
    Tong, Xiaohong
    Tian, Tian
    Lyu, Bo
    Wang, Mengmeng
    Wang, Huan
    Jiang, Lianzhou
    FOOD CHEMISTRY, 2022, 384
  • [50] Effect of non-covalent and covalent complexation of (-)-epigallocatechin gallate with soybean protein isolate on protein structure and in vitro digestion characteristics
    Zhou, Si-Duo
    Lin, Yan-Fei
    Xu, Xiao
    Meng, Ling
    Dong, Ming-Sheng
    FOOD CHEMISTRY, 2020, 309 (309)
12345