Resources and procedures in the treatment of heavy menstrual bleeding with the levonorgestrel-releasing intrauterine system (LNG-IUS) or hysterectomy in Brazil

被引:16
作者
Valeria Bahamondes, M. [1 ,2 ]
de Lima, Yuri [1 ,2 ]
Teich, Vanessa [3 ]
Bahamondes, Luis [1 ,2 ]
Monteiro, Ilza [1 ,2 ]
机构
[1] Univ Campinas UNICAMP, Sch Med Sci, Human Reprod Unit, Dept Obstet & Gynecol, BR-13084971 Campinas, SP, Brazil
[2] Natl Inst Hormones & Womens Hlth, BR-13084971 Campinas, SP, Brazil
[3] MedInsight, BR-04564040 Sao Paulo, Brazil
关键词
Pharmacoeconomics; Levonorgestrel-releasing intrauterine system; Mirena; Heavy menstrual bleeding; Hysterectomy; COST-EFFECTIVENESS; MENORRHAGIA; ABLATION; WOMEN; UTILITY; TRIAL;
D O I
10.1016/j.contraception.2011.12.005
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Background: Heavy menstrual bleeding (HMB) is the most common complaint of women seeking gynecological care. Treatments included surgical or medical options including hysterectomy and the levonorgestrel-releasing intrauterine system (LNG-IUS) due to the profound suppression of endometrial growth that intrauterine LNG exerts which results in amenorrhea or in a reduction of blood loss. Objective: The study was conducted to evaluate the resources and procedures involved in inserting an LNG-IUS compared to performing hysterectomy in women with HMB in a public sector hospital in Brazil. Study design: Two cohorts of women were studied: women who accepted an LNG-IUS (n=124) and matched women who underwent hysterectomy on the same day (n=122). We evaluate the number of procedures carried out in each group of women, including those performed before the decision was made to insert an LNG-IUS or to perform hysterectomy, the insertion of the device itself and the surgical procedure, in addition to the procedures and complications registered up to I year after LNG-IUS insertion or hysterectomy. Results: Age and the duration of HMB were significantly lower in the LNG-IUS acceptors than women at the hysterectomy group. The numbers of gynecological consultations and Pap smears were similar in both groups; however, women in the hysterectomy group also underwent laboratory tests, ultrasonography, chest X-ray and electrocardiogram. In the hysterectomy group, the main complications were hemorrhage (six), bladder/bowel perforation (four), complications with anesthesia (one), ureteral reimplantation required (one) and abdominal pain (two). At I year, HMB was controlled in 83.1% of women in the LNG-IUS group, and 106 women continued with the device. Conclusions: Both treatments were effective in HMB control. Fewer resources and complications were observed in LNG-IUS acceptors when compared to hysterectomy. The LNG-IUS represents a good strategy for reducing the number of hysterectomies and the resources required for women with HMB. (C) 2012 Elsevier Inc. All rights reserved.
引用
收藏
页码:244 / 250
页数:7
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