Ruthenium-catalyzed cycloaddition of alkynes and organic azides

被引：989

作者：

Zhang, L

Chen, XG

Xue, P

Sun, HHY

Williams, ID

Sharpless, KB

Fokin, VV ^{[1
]}

Jia, GC

机构：

[1] Hong Kong Univ Sci & Technol, Dept Chem, Kowloon, Hong Kong, Peoples R China

[2] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA

[3] Scripps Res Inst, Skaggs Inst Chem Biol, La Jolla, CA 92037 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2005年 / 127卷 / 46期

关键词：

D O I：

10.1021/ja054114s

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Cp*RuCl(PPh3)2 is an effective catalyst for the regioselective "fusion" of organic azides and terminal alkynes, producing 1,5-disubstituted 1,2,3-triazoles. Internal alkynes also participate in this catalysis, resulting in fully substituted 1,2,3-triazoles. Copyright © 2005 American Chemical Society.

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页码：15998 / 15999

页数：2

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