An Efficient One-Pot Synthesis of Substituted 1H-Naphtho[2,1-b]pyrans and 4H-1-Benzopyrans (=Chromenes) under Solvent-Free Microwave-Irradiation Conditions

被引：19

作者：

Shekhar, Adimulam Chandra ^{[1
]}

Kumar, Akula Ravi ^{[1
]}

Sathaiah, Gangaram ^{[1
]}

Raju, Kengiri ^{[1
]}

Rao, Pamulaparthy Shanthan ^{[1
]}

Sridhar, Madabhushi ^{[1
]}

Narsaiah, Banda ^{[1
]}

Srinivas, Punnamraju Venkata Satya Surya ^{[1
]}

Sridhar, Balasubramanian ^{[2
]}

机构：

[1] Indian Inst Chem Technol, Fluoroorgan Div, Hyderabad 500607, Andhra Pradesh, India

[2] Indian Inst Chem Technol, Dept Xray Crystallog, Hyderabad 500607, Andhra Pradesh, India

来源：

HELVETICA CHIMICA ACTA | 2012年 / 95卷 / 03期

关键词：

Benzo[f]chromenes; 1H-Naphtho[2; 1-b]pyrans; Multicomponent reactions; 4H-1-Benzopyrans; Molecular sieves; Microwave irradiation; HETEROCYCLIC SYNTHESIS; 2-AMINO-2-CHROMENES; DERIVATIVES; CINNAMONITRILES; NITRILES; WATER;

D O I：

10.1002/hlca.201100332

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A facile heterogeneous synthesis of 3-amino-1-aryl-1H-naphtho[2,1-b]pyran and 2-amino-4-aryl-4H-1-benzopyran derivatives 3 and 5, respectively, was carried out efficiently by one-pot three-component coupling of an aromatic aldehyde 1, an active methylene compound 2, and naphthalen-2-ol or a phenol 4 in the presence of 5-angstrom molecular sieves under solvent-free microwave-irradiation conditions (Scheme 1 and 2, Tables 1 and 2). The catalyst was recovered and recycled (Table 3).

引用

页码：502 / 508

页数：7

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