Redox-Neutral Ni-Catalyzed sp3C-H Alkylation ofα-Olefins withUnactivated Alkyl Bromides

被引：23

作者：

Buendia, Mikkel B. ^{[1
]}

Higginson, Bradley ^{[2
,3
]}

Kegnaes, Soren ^{[1
]}

Kramer, Soren ^{[1
]}

Martin, Ruben ^{[2
,4
]}

机构：

[1] Tech Univ Denmark, Dept Chem, DK-2800 Lyngby, Denmark

[2] Barcelona Inst Sci & Technol, Inst Chem Res Catalonia ICIQ, Tarragona 43007, Spain

[3] Univ Rovira & Virgili, Dept Quim, Tarragona 43007, Spain

[4] ICREA, Barcelona 08010, Spain

来源：

ACS CATALYSIS | 2022年 / 12卷 / 07期

关键词：

nickel; photochemistry; cross-coupling; alkylation; olefin functionalization; C-H ALKYLATION; ASYMMETRIC HYDROFUNCTIONALIZATION; ALLYLIC OXIDATION; HECK ARYLATIONS; FUNCTIONALIZATION; ALKENES; PHOTOREDOX; ALCOHOLS; BONDS; LIGHT;

D O I：

10.1021/acscatal.2c01057

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A light-induced redox-neutral Ni-catalyzed sp3C-H alkylation of unactivated alkenes with alkyl bromides possessing beta-hydrogens is described herein. The method is distinguished by itssimplicity, wide scope, and exquisite regio- and chemoselectivityprofile, thus offering an entry point to forge sp3-sp3architectures.

引用

页码：3815 / 3820

页数：6

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