Metal-Free One-Pot Synthesis of N,N′-Diarylamidines and N-Arylbenzimidazoles from Arenediazonium Salts, Nitriles, and Free Anilines

被引：31

作者：

Youn, So Won ^{[1
]}

Lee, Eun Mi

机构：

[1] Hanyang Univ, Ctr New Direct Organ Synth, Dept Chem, Seoul 04763, South Korea

来源：

ORGANIC LETTERS | 2016年 / 18卷 / 21期

基金：

新加坡国家研究基金会;

关键词：

C-H AMINATION; DIAZONIUM SALTS; BENZIMIDAZOLE DERIVATIVES; IRIDIUM(III) COMPLEXES; PHENYL CATIONS; BOND FORMATION; LEAVING GROUP; AMIDINES; ARYLATION; CHEMISTRY;

D O I：

10.1021/acs.orglett.6b02994

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly efficient and facile metal-free, one-pot reaction has been developed to afford diversely substituted N-arylbenzimidazoles through chemoselective in situ generation of N,N'-diarylamidines from arenediazonium salts, nitrites, and free anilines. The advantages of this protocol consist of the operationally easy and simple one-pot procedure under metal-free and mild conditions, the direct use of inexpensive and commercially available chemicals, and thus, a cost-effective and greener process.

引用

页码：5728 / 5731

页数：4

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