Native ETV6 deletions accompanied by ETV6-RUNX1 rearrangements are associated with a favourable prognosis in childhood acute lymphoblastic leukaemia: a candidate for prognostic marker

被引:12
作者
Ko, Dae-Hyun [1 ]
Jeon, Yongbum [1 ]
Kang, Hyoung Jin [2 ]
Park, Kyung Duk [2 ]
Shin, Hee Young [2 ]
Kim, Hyun Kyung [1 ]
Cho, Han-Ik [1 ]
Ahn, Hyo Seop [2 ]
Lee, Dong Soon [1 ]
机构
[1] Seoul Natl Univ, Coll Med, Dept Lab Med, Seoul, South Korea
[2] Seoul Natl Univ, Coll Med, Canc Res Inst, Dept Paediat, Seoul, South Korea
关键词
acute lymphoblastic leukaemia; ETV6-RUNX1; rearrangements; native ETV6 deletion; prognosis; FUSION;
D O I
10.1111/j.1365-2141.2011.08729.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:530 / 533
页数:5
相关论文
共 10 条
  • [1] Incidence and relevance of secondary chromosome abnormalities in childhood TEL/AML1+ acute lymphoblastic leukemia:: an interphase FISH analysis
    Attarbaschi, A
    Mann, G
    König, M
    Dworzak, MN
    Trebo, MM
    Mühlegger, N
    Gadner, H
    Haas, OA
    [J]. LEUKEMIA, 2004, 18 (10) : 1611 - 1616
  • [2] Carroll William L, 2003, Hematology Am Soc Hematol Educ Program, P102
  • [3] Prognostic Significance of TEL/AML1 Rearrangement and Its Additional Genetic Changes in Korean Childhood Precursor B-Acute Lymphoblastic Leukemia
    Chung, Hee Young
    Kim, Kyung-Hee
    Jun, Kyung Ran
    Jang, Seongsoo
    Park, Chan-Jeoung
    Chi, Hyun-Sook
    Im, Ho Joon
    Seo, Jong Jin
    Seo, Eul-Ju
    [J]. KOREAN JOURNAL OF LABORATORY MEDICINE, 2010, 30 (01): : 1 - 8
  • [4] The TEL-AML1 fusion accompanied by loss of the untranslocated TEL allele in B-precursor acute lymphoblastic leukaemia of childhood
    Kempski, HM
    Sturt, NT
    [J]. LEUKEMIA & LYMPHOMA, 2000, 40 (1-2) : 39 - +
  • [5] Low incidence of TEL/AML1 fusion and TEL deletion in Korean childhood acute leukemia by extra-signal fluorescence in situ hybridization
    Park, KU
    She, CJ
    Shin, HY
    Ahn, HS
    Kim, CJ
    Cho, BK
    Cho, HI
    Lee, DS
    [J]. CANCER GENETICS AND CYTOGENETICS, 2001, 126 (01) : 73 - 77
  • [6] HIGH-FREQUENCY OF T(12-21) IN CHILDHOOD B-LINEAGE ACUTE LYMPHOBLASTIC-LEUKEMIA
    ROMANA, SP
    POIREL, H
    LECONIAT, M
    FLEXOR, MA
    JONVEAUX, MMP
    MACINTYRE, EA
    BERGER, R
    BERNARD, OA
    [J]. BLOOD, 1995, 86 (11) : 4263 - 4269
  • [7] Risk- and response-based classification of childhood B-precursor acute lymphoblastic leukemia: a combined analysis of prognostic markers from the Pediatric Oncology Group (POG) and Children's Cancer Group (CCG)
    Schultz, Kirk R.
    Pullen, D. Jeanette
    Sather, Harland N.
    Shuster, Jonathan J.
    Devidas, Meenakshi
    Borowitz, Michael J.
    Carrol, Andrew J.
    Heerema, Nyla A.
    Rubnitz, Jeff Rey E.
    Loh, Mignon L.
    Raetz, Elizabeth A.
    Winick, Naomi J.
    Hunger, Stephen P.
    Carroll, William L.
    Gaynon, Paul S.
    Camitta, Bruce M.
    [J]. BLOOD, 2007, 109 (03) : 926 - 935
  • [8] Tel induces a G1 arrest and suppresses Ras-induced transformation
    Van Rompaey, L
    Potter, M
    Adams, C
    Grosveld, G
    [J]. ONCOGENE, 2000, 19 (46) : 5244 - 5250
  • [9] Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells
    Viale, Andrea
    De Franco, Francesca
    Orleth, Annette
    Cambiaghi, Valeria
    Giuliani, Virginia
    Bossi, Daniela
    Ronchini, Chiara
    Ronzoni, Simona
    Muradore, Ivan
    Monestiroli, Silvia
    Gobbi, Alberto
    Alcalay, Myriam
    Minucci, Saverio
    Pelicci, Pier Giuseppe
    [J]. NATURE, 2009, 457 (7225) : 51 - U52
  • [10] Molecular cytogenetic analysis of gene rearrangements in childhood acute lymphoblastic leukemia
    Woo, HY
    Kim, DW
    Park, H
    Seong, KW
    Koo, HH
    Kim, SH
    [J]. JOURNAL OF KOREAN MEDICAL SCIENCE, 2005, 20 (01) : 36 - 41