Synthesis of two naturally occurring 3-methyl-2,5-dihydro-1-benzoxepin carboxylic acids

被引：46

作者：

Yamaguchi, S ^{[1
]}

Tsuchida, N ^{[1
]}

Miyazawa, M ^{[1
]}

Hirai, Y ^{[1
]}

机构：

[1] Toyama Univ, Fac Sci, Dept Chem, Toyama 9308555, Japan

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2005年 / 70卷 / 19期

关键词：

D O I：

10.1021/jo050550l

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two naturally occurring 3-methyl-2,5-dihydro-1-benzoxepin carboxylic acids, 6-hydroxy-3-methyl-8-(phenylethyl)-2,5-dihydro-1-benzoxepin-9-carboxylic acid (radulanin E) (1) and 9-hydroxy-3methyl-2,5-dihydro-1-benzoxepin-7-carboxylic acid (2), were synthesized using Stille coupling followed by Mitsunobu cyclization.

引用

页码：7505 / 7511

页数：7

共 21 条

[1] BIBENZYLS FROM RADULA-TOKIENSIS AND RADULA-JAPONICA
ASAKAWA, Y
TAKEDA, R
TOYOTA, M
TAKEMOTO, T
[J]. PHYTOCHEMISTRY, 1981, 20 (04) : 858 - 859
[2] 7 NEW BIBENZYLS AND A DIHYDROCHALCONE FROM RADULA-VARIABILIS
ASAKAWA, Y
TOYOTA, M
TAKEMOTO, T
[J]. PHYTOCHEMISTRY, 1978, 17 (11) : 2005 - 2010
[3] NEW BIBENZYLS FROM RADULA-COMPLANATA
ASAKAWA, Y
KUSUBE, E
TAKEMOTO, T
SUIRE, C
[J]. PHYTOCHEMISTRY, 1978, 17 (12) : 2115 - 2117
[4] CHEMOSYSTEMATICS OF THE BRYOPHYTES .12. NOVEL BIBENZYL DERIVATIVES AND ENT-CUPARENE-TYPE SESQUITERPENOIDS FROM RADULA SPECIES
ASAKAWA, Y
TAKIKAWA, K
TOYOTA, M
TAKEMOTO, T
[J]. PHYTOCHEMISTRY, 1982, 21 (10) : 2481 - 2490
[5] CYCLOPROPANOCHROMAN DERIVATIVES FROM THE LIVERWORT RADULA-JAVA']JAVANICA
ASAKAWA, Y
KONDO, K
TORI, M
[J]. PHYTOCHEMISTRY, 1991, 30 (01) : 325 - 328
[6] CHEMOSYSTEMATICS OF BRYOPHYTES .40. PRENYL BIBENZYLS FROM THE LIVERWORTS RADULA-PERROTTETII AND RADULA-COMPLANATA
ASAKAWA, Y
HASHIMOTO, T
TAKIKAWA, K
TORI, M
OGAWA, S
[J]. PHYTOCHEMISTRY, 1991, 30 (01) : 235 - 251
[7] PROTOCATECHUIC ACID-DERIVATIVES FROM HEMIZONIA-LOBBII
BREUER, M
LEEDER, G
PROKSCH, P
BUDZIKIEWICZ, H
[J]. PHYTOCHEMISTRY, 1986, 25 (02) : 495 - 497
[8] Substitution in vicinal trisubstituted benzene derivatives. Part I.
Davies, W
[J]. JOURNAL OF THE CHEMICAL SOCIETY, 1923, 123 : 1575 - 1593
[9] DEAN FM, 1967, TETRAHEDRON LETT, P3459, DOI 10.1016/S0040-4039(01)89821-X
[10] EXTRACTIVES FROM EAST AFRICAN TIMBERS .2. PTAEROXYLON OBLIQUUM
DEAN, FM
TAYLOR, DAH
[J]. JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC, 1966, (01): : 114 - &

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