Pulmonary hypertension confirmed histologically five months prior to scleroderma renal crisis onset

被引:1
作者
Watanabe, Ryu [1 ]
Nakaya, Izaya [1 ]
Yahata, Mayumi [1 ]
Takahashi, Tohru [2 ]
Sasajima, Tomomi [3 ]
Takeuchi, Kenichi [3 ]
Oura, Hiroyuki [4 ]
Sakuma, Tsutomu [5 ]
Tomichi, Nobukazu [5 ]
Mori, Yasuki [6 ]
Soma, Jun [1 ]
机构
[1] Iwate Cent Prefectural Hosp, Dept Nephrol, Morioka, Iwate 0200060, Japan
[2] Iwate Cent Prefectural Hosp, Dept Cardiol, Morioka, Iwate 0200060, Japan
[3] Iwate Cent Prefectural Hosp, Dept Respiratol, Morioka, Iwate 0200060, Japan
[4] Iwate Cent Prefectural Hosp, Dept Resp Surg, Morioka, Iwate 0200060, Japan
[5] Iwate Cent Prefectural Hosp, Dept Pathol, Morioka, Iwate 0200060, Japan
[6] Iwate Cent Prefectural Hosp, Dept Dermatol, Morioka, Iwate 0200060, Japan
关键词
Acute kidney injury; Endothelial damage; Limited cutaneous scleroderma; Lung fibrosis; Prostanoids; CASE-CONTROL AUTOPSY; SYSTEMIC-SCLEROSIS; ARTERIAL-HYPERTENSION; MORPHOMETRY; DISEASE;
D O I
10.1007/s10165-010-0390-7
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 69-year-old man presented shortness of breath and acute renal failure. He had undergone pulmonary partial resection for lung cancer 5 months prior. On examination, severe hypertension, skin sclerosis of his forearms, and anticentromere antibody were observed. A renal biopsy specimen showed characteristic findings for scleroderma renal crisis, and a right heart catheterization revealed severe pulmonary arterial hypertension. Re-examination of the resected lung specimen revealed sclerodermatous vascular involvement was present.
引用
收藏
页码:320 / 324
页数:5
相关论文
共 16 条
[1]  
ALSABBAGH MR, 1989, J RHEUMATOL, V16, P1038
[2]   Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease -: A randomized, controlled trial [J].
Badesch, DB ;
Tapson, VF ;
McGoon, MD ;
Brundage, BH ;
Rubin, LJ ;
Wigley, FM ;
Rich, S ;
Barst, RJ ;
Barrett, PS ;
Kral, KM ;
Jöbsis, MM ;
Loyd, JE ;
Murali, S ;
Frost, A ;
Girgis, R ;
Bourge, RC ;
Ralph, DD ;
Elliott, CG ;
Hill, NS ;
Langleben, D ;
Schilz, RJ ;
McLaughlin, VV ;
Robbins, IM ;
Groves, BM ;
Shapiro, S ;
Medsger, TA ;
Gaine, SP ;
Horn, E ;
Decker, JC ;
Knobil, K .
ANNALS OF INTERNAL MEDICINE, 2000, 132 (06) :425-+
[3]   Mechanisms of disease: Pulmonary arterial hypertension [J].
Farber, HW ;
Loscalzo, J .
NEW ENGLAND JOURNAL OF MEDICINE, 2004, 351 (16) :1655-1665
[4]  
Gündüz OH, 2001, ARTHRITIS RHEUM, V44, P1663, DOI 10.1002/1529-0131(200107)44:7<1663::AID-ART290>3.0.CO
[5]  
2-C
[6]  
Joglekar A, 2006, J RHEUMATOL, V33, P61
[7]  
LEROY EC, 1988, J RHEUMATOL, V15, P202
[8]   ANTITOPOISOMERASE-I MONOCLONAL AUTOANTIBODIES FROM SCLERODERMA PATIENTS AND TIGHT SKIN MOUSE INTERACT WITH SIMILAR EPITOPES [J].
MURYOI, T ;
KASTURI, KN ;
KAFINA, MJ ;
CRAM, DS ;
HARRISON, LC ;
SASAKI, T ;
BONA, CA .
JOURNAL OF EXPERIMENTAL MEDICINE, 1992, 175 (04) :1103-1109
[9]  
Pandey JP, 1998, ARTHRITIS RHEUM, V41, P10, DOI 10.1002/1529-0131(199801)41:1<10::AID-ART2>3.3.CO
[10]  
2-G