Three new ester glycosides with cytotoxic activity from the seeds of Caesalpinia sappan

被引:5
|
作者
Wang, Min [1 ]
Tan, Juan [2 ]
Chen, Jun [1 ]
Xie, Tian [3 ]
Lin, Liang-Mo [1 ]
Zhong, Li-Li [1 ]
Cai, Xing-Jun [3 ]
Wu, Qiong-Shi [1 ]
机构
[1] Hainan Med Univ, Hainan Gen Hosp, Dept Pharm, Hainan Affiliated Hosp, Haikou, Hainan, Peoples R China
[2] Wuhan Univ, Dept Pharm, Renmin Hosp, Wuhan, Peoples R China
[3] Hainan Med Univ, Hainan Genaral Hosp, Dept Resp & Crit Care Med, Hainan Affiliated Hosp, Haikou, Hainan, Peoples R China
关键词
Caesalpinia sappan; seeds; ester glycosides; cytotoxicity; CASSANE DITERPENES; HEARTWOOD; BRIDGE;
D O I
10.1080/14786419.2020.1721488
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Three new ester glycosides, named as Caesateroside A (1), Caesateroside B (2) and Caesateroside C (3) were obtained from the seeds of Caesalpinia sappan. The new structures of compounds 1-3 were elucidated by analyzing their 1 D NMR, 2 D NMR and HR-ESI-MS spectra. Compounds 1-3 showed weak-moderate cytotoxicity against Hela and HepG-2 human cancer cell lines.
引用
收藏
页码:4409 / 4416
页数:8
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