Three new ester glycosides with cytotoxic activity from the seeds of Caesalpinia sappan

被引:5
|
作者
Wang, Min [1 ]
Tan, Juan [2 ]
Chen, Jun [1 ]
Xie, Tian [3 ]
Lin, Liang-Mo [1 ]
Zhong, Li-Li [1 ]
Cai, Xing-Jun [3 ]
Wu, Qiong-Shi [1 ]
机构
[1] Hainan Med Univ, Hainan Gen Hosp, Dept Pharm, Hainan Affiliated Hosp, Haikou, Hainan, Peoples R China
[2] Wuhan Univ, Dept Pharm, Renmin Hosp, Wuhan, Peoples R China
[3] Hainan Med Univ, Hainan Genaral Hosp, Dept Resp & Crit Care Med, Hainan Affiliated Hosp, Haikou, Hainan, Peoples R China
关键词
Caesalpinia sappan; seeds; ester glycosides; cytotoxicity; CASSANE DITERPENES; HEARTWOOD; BRIDGE;
D O I
10.1080/14786419.2020.1721488
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Three new ester glycosides, named as Caesateroside A (1), Caesateroside B (2) and Caesateroside C (3) were obtained from the seeds of Caesalpinia sappan. The new structures of compounds 1-3 were elucidated by analyzing their 1 D NMR, 2 D NMR and HR-ESI-MS spectra. Compounds 1-3 showed weak-moderate cytotoxicity against Hela and HepG-2 human cancer cell lines.
引用
收藏
页码:4409 / 4416
页数:8
相关论文
共 50 条
  • [11] Guided Isolation of New Cytotoxic Cassane Diterpenoids from Caesalpinia sappan
    Jin, Yue
    Tong, Zi-Wei
    Gao, Hui-Yuan
    Wu, Zhao-Hua
    CHEMISTRY & BIODIVERSITY, 2023, 20 (05)
  • [12] Bioactive cassane diterpenoids from the seeds of Caesalpinia sappan
    Zhu, Nai-Liang
    Xu, Xu-Dong
    Hu, Mei-Geng
    Sun, Zhong-Hao
    Wu, Tong-Yu
    Yuan, Jing-Quan
    Wu, Hai-Feng
    Tian, Yu
    Li, Peng-Fei
    Yang, Jun-Shan
    Ma, Guo-Xu
    PHYTOCHEMISTRY LETTERS, 2017, 22 : 113 - 116
  • [13] New Cassane Diterpenoids from Caesalpinia sappan and Their Antiplasmodial Activity
    Zhu, Nai-Liang
    Sun, Zhong-Hao
    Hu, Mei-Geng
    Wu, Tong-Yu
    Yuan, Jing-Quan
    Wu, Hai-Feng
    Tian, Yu
    Li, Peng-Fei
    Yang, Jun-Shan
    Ma, Guo-Xu
    Xu, Xu-Dong
    MOLECULES, 2017, 22 (10):
  • [14] Two new cassane diterpenoids from the seeds of Caesalpinia sappan Linn.
    Zhang Jing-Yu
    Wu Fei-Hua
    Qu Wei
    Liang Jing-Yu
    CHINESE JOURNAL OF NATURAL MEDICINES, 2012, 10 (03): : 218 - 221
  • [15] Antioxidant Activity In Vitro of Three Constituents from Caesalpinia sappan L
    胡珺
    闫晓玲
    王伟
    吴昊
    花雷
    杜力军
    TsinghuaScienceandTechnology, 2008, (04) : 474 - 479
  • [16] Two new cassane-type diterpenoids from the seeds of Caesalpinia sappan
    Yuanting, Jiang
    Ruikang, Han
    Yang, Liu
    Hanqiao, Liang
    NATURAL PRODUCT RESEARCH, 2022, 36 (08) : 2078 - 2084
  • [17] A new homoisoflavan from Caesalpinia sappan
    Zhao, Huanxin
    Bai, Hong
    Wang, Yuanshu
    Li, Wei
    Koike, Kazuo
    JOURNAL OF NATURAL MEDICINES, 2008, 62 (03) : 325 - 327
  • [18] A new homoisoflavan from Caesalpinia sappan
    Huanxin Zhao
    Hong Bai
    Yuanshu Wang
    Wei Li
    Kazuo Koike
    Journal of Natural Medicines, 2008, 62 : 325 - 327
  • [19] Cytotoxic and Pro-Apoptotic Effects of Cassane Diterpenoids from the Seeds of Caesalpinia sappan in Cancer Cells
    Bao, Han
    Zhang, Le-Le
    Liu, Qian-Yu
    Feng, Lu
    Ye, Yang
    Lu, Jin-Jian
    Lin, Li-Gen
    MOLECULES, 2016, 21 (06)
  • [20] New Cardenolide Glycosides from the Seeds of Digitalis purpurea and Their Cytotoxic Activity
    Kuroda, Minpei
    Kubo, Satoshi
    Matsuo, Yukiko
    Atou, Tomomi
    Satoh, Junichi
    Fujino, Tomofumi
    Hayakawa, Makio
    Mimaki, Yoshihiro
    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2013, 77 (06) : 1186 - 1192