Design of high-ductile medium entropy alloys for dental implants

被引：82

作者：

Wang, Shubin ^{[1
]}

Wu, Dongle ^{[2
,3
]}

She, Huan ^{[1
,2
,4
]}

Wu, Mingxu ^{[1
]}

Shu, Da ^{[1
]}

Dong, Anping ^{[1
]}

Lai, Hongchang ^{[2
,3
]}

Sun, Baode ^{[1
]}

机构：

[1] Shanghai Jiao Tong Univ, Sch Mat Sci & Engn, Shanghai Key Lab Adv High Temp Mat & Precis Formi, Shanghai 200240, Peoples R China

[2] Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 9, Coll Stomatol, Dept Dent Implantol,Sch Med, Shanghai 200011, Peoples R China

[3] Shanghai Res Inst Stomatol, Natl Clin Res Ctr Oral Dis, Shanghai Key Lab Stomatol, Shanghai 200011, Peoples R China

[4] Shanghai Inst Technol, Sch Mech Engn, Shanghai 201418, Peoples R China

来源：

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS | 2020年 / 113卷

基金：

中国国家自然科学基金;

关键词：

Medium entropy alloys; Tensile properties; Biocompatibility; Human gingival fibroblasts; Gene expression; MECHANICAL-PROPERTIES; TENSILE PROPERTIES; YOUNGS MODULUS; IN-VITRO; MICROSTRUCTURE; TITANIUM; BEHAVIOR; BIOCOMPATIBILITY; NIOBIUM;

D O I：

10.1016/j.msec.2020.110959

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

Developing new materials with high strength and ductility, low modulus and high biocompatibility is a continuing demand in the field of surgical implants. Inspired by the high-entropy design philosophy, two medium entropy alloys (MEAs), i.e. equiatomic TiZrHf and equi-weight Ti40Zr20Hf10Nb20Ta10 were designed and their mechanical properties and biocompatibility were assessed. Both the single-phase hexagonal close-packed (HCP) structured TiZrHf alloy and the single-phase body-centered cubic (BCC) structured Ti40Zr20Hf10Nb20Ta10 alloy show high strength-ductility combinations close to commercial Ti-6Al-4V wrought alloy and remarkably lower young's modulus than commercial pure titanium (CP-Ti) and Ti-6Al-4V. From the aspects of adhesion, proliferation, toxicity and related gene expression of human gingival fibroblasts (HGFs), the Ti40Zr20Hf10Nb20Ta10 alloy exhibits distinctively better biocompatibility than that of CP-Ti while the TiZrHf shows only slightly better biocompatibility as compared with CP-Ti. These results indicate that these two ductile MEAs are potential candidates for dental application.

引用

页数：10

共 44 条

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