Site-Specific Chemical Modification of Peptide and Protein by Thiazolidinediones

被引：31

作者：

Wang, Peng

Zhang, Shumei

Meng, Qiuyue

Liu, Ying

Shang, Luqing ^{[1
]}

Yin, Zheng

机构：

[1] Nankai Univ, Coll Pharm, Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300071, Peoples R China

来源：

ORGANIC LETTERS | 2015年 / 17卷 / 06期

基金：

中国国家自然科学基金;

关键词：

BIOMIMETIC TRANSAMINATION REACTION; BIOORTHOGONAL CHEMISTRY; ALDOL REACTIONS; OXIME LIGATION; BIOCONJUGATION; ALKYLATION; CYSTEINES; HYDRAZONE; CATALYSIS; ALDEHYDE;

D O I：

10.1021/acs.orglett.5b00005

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A direct aldol reaction employing 2,4-thiazolidinediones as nucleophilic donors was performed to modify peptides and protein under mild conditions. Various functional groups could be readily introduced into protein without conformation change.

引用

页码：1361 / 1364

页数：4

共 50 条

[1] Challenges in the use of sortase and other peptide ligases for site-specific protein modification
Morgan, Holly E.
Turnbull, W. Bruce
Webb, Michael E.
CHEMICAL SOCIETY REVIEWS, 2022, 51 (10) : 4121 - 4145
[2] Site-specific chemical modification of phage particles
Saleh, Lana
Ramspacher, Caroline
Correa, Ivan R., Jr.
Noren, Christopher J.
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2011, 241
[3] Site-specific protein modification: advances and applications
Foley, Timothy L.
Burkart, Michael D.
CURRENT OPINION IN CHEMICAL BIOLOGY, 2007, 11 (01) : 12 - 19
[4] Chemoenzymatic methods for site-specific protein modification
Rabuka, David
CURRENT OPINION IN CHEMICAL BIOLOGY, 2010, 14 (06) : 790 - 796
[5] Site-Specific Protein Modification with Reducing Carbohydrates
Wu, Qifan
Dong, Weidong
Miao, Hui
Wang, Qian
Dong, Suwei
Xuan, Weimin
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 61 (19)
[6] A NEW TOOL FOR SITE-SPECIFIC CHEMICAL MODIFICATION OF RNA
Sasaki, Shigeki
Shibata, Atsushi
Inaba, Natsuki
Onizuka, Kazumitsu
Taniguchi, Yosuke
NUCLEIC ACID THERAPEUTICS, 2011, 21 (05) : A24 - A25
[7] Structural basis for the site-specific chemical modification of proteins
Schneider, Sabine
Fluegel, Veronika
Carell, Thomas
Gattner, Michael
Vrabel, Milan
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2013, 69 : S325 - S326
[8] Chemical methods for protein site-specific ubiquitination
Gui, Weijun
Davidson, Gregory A.
Zhuang, Zhihao
RSC CHEMICAL BIOLOGY, 2021, 2 (02): : 450 - 467
[9] SITE-SPECIFIC CHEMICAL MODIFICATION OF A STREPTOCOCCAL ANTIBODY-BINDING SITE
PITNER, JB
LINN, CP
MIZE, PD
MALINOWSKI, DP
JOURNAL OF CELLULAR BIOCHEMISTRY, 1994, : 266 - 266
[10] Enabling Wittig reaction on site-specific protein modification
Han, Ming-Jie
Xiong, De-Cai
Ye, Xin-Shan
CHEMICAL COMMUNICATIONS, 2012, 48 (90) : 11079 - 11081

← 1 2 3 4 5 →