Hydrogen sulfide: physiological properties and therapeutic potential in ischaemia

被引：47
作者：
Bos, Eelke M. [1 ,2 ]
van Goor, Harry [1 ]
Joles, Jaap A. [3 ]
Whiteman, Matthew [4 ]
Leuvenink, Henri G. D. [2 ]
机构：
[1] Univ Groningen, Univ Med Ctr Groningen, Dept Pathol & Med Biol, Groningen, Netherlands
[2] Univ Groningen, Univ Med Ctr Groningen, Dept Surg, Groningen, Netherlands
[3] Univ Med Ctr Utrecht, Dept Hypertens & Nephrol, Utrecht, Netherlands
[4] Univ Exeter, Peninsula Med Sch, Exeter, Devon, England
来源：
BRITISH JOURNAL OF PHARMACOLOGY | 2015年 / 172卷 / 06期
关键词：
CYSTATHIONINE-BETA-SYNTHASE; GAMMA-LYASE EXPRESSION; INDUCED HEART-FAILURE; ANIMATION-LIKE STATE; REPERFUSION INJURY; OXIDATIVE STRESS; NITRIC-OXIDE; CONCISE GUIDE; 3-MERCAPTOPYRUVATE SULFURTRANSFERASE; RENAL ISCHEMIA/REPERFUSION;
D O I：
10.1111/bph.12869
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Hydrogen sulfide (H2S) has become a molecule of high interest in recent years, and it is now recognized as the third gasotransmitter in addition to nitric oxide and carbon monoxide. In this review, we discuss the recent literature on the physiology of endogenous and exogenous H2S, focusing upon the protective effects of hydrogen sulfide in models of hypoxia and ischaemia. Linked ArticlesThis article is part of a themed section on Pharmacology of the Gasotransmitters. To view the other articles in this section visit
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收藏
页码：1479 / 1493
页数：15
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