Successful treatment with IVIg therapy of diabetes-associated scleredema severe progressive case and review of the literature

被引：10

作者：

Kennemer, Caroline ^{[1
]}

Pavlidakey, Peter ^{[2
]}

Sami, Naveed ^{[3
]}

机构：

[1] Univ Alabama Birmingham, Sch Med, Birmingham, AL USA

[2] Univ Alabama Birmingham, Dept Dermatol, Birmingham, AL 35294 USA

[3] Univ Cent Florida, Dept Med, Orlando, FL 32816 USA

来源：

DERMATOLOGIC THERAPY | 2017年 / 30卷 / 04期

关键词：

intravenous immunoglobulin; IVIg; scleredema; therapy; treatment; INTRAVENOUS IMMUNOGLOBULIN; ADULTORUM BUSCHKE; SCLEROMYXEDEMA;

D O I：

10.1111/dth.12504

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Scleredema is a deposition disorder which presents as diffuse, symmetric, non-pitting skin induration from dermal deposits of glycosaminoglycans (mucins). It classically affects the upper back and posterior neck, often causing skin tightness and decreased range of motion. In most patients the clinical course is chronic and treatment options are limited. We report a case of a patient diagnosed with scleredema associated with longstanding insulin dependent diabetes who was treated successfully with IVIg. Additionally, we have reviewed the literature reporting other patients with scleredema treated with IVIg.

引用

页数：3

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